85058-11-3Relevant articles and documents
Indium-mediated cleavage of the trityl group from protected alcohols and diols
Behloul, Cherif,Chouti, Aicha,Guijarro, David,Foubelo, Francisco,Nájera, Carmen,Yus, Miguel
, p. 7937 - 7941 (2016)
The reaction of primary, secondary, allylic and benzylic trityl ethers with indium powder in MeOH/NH4Cl led to reductive cleavage of the trityl-oxygen bond, affording the corresponding alcohols in good to excellent yield under very mild reaction conditions. The detritylation process could successfully be extended to mono and detritylated diols. This methodology represents a new and efficient detritylation procedure under mild reaction conditions.
