85078-43-9

Basic information

• Product Name: 3-[5-(chloromethyl)-1,3,4-oxadiazol-2-yl]-1H-indole
• Synonyms: 3-[5-(chloromethyl)-1,3,4-oxadiazol-2-yl]-1H-indole
• CAS NO: 85078-43-9
• Molecular Formula: C11H8ClN3O
• Molecular Weight: 233.65
• Mol File: 85078-43-9.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-[5-(chloromethyl)-1,3,4-oxadiazol-2-yl]-1H-indole(CAS DataBase Reference)
• NIST Chemistry Reference: 3-[5-(chloromethyl)-1,3,4-oxadiazol-2-yl]-1H-indole(85078-43-9)
• EPA Substance Registry System: 3-[5-(chloromethyl)-1,3,4-oxadiazol-2-yl]-1H-indole(85078-43-9)

Safety Data

• Hazardous Substances Data: 85078-43-9(Hazardous Substances Data)

Upstream product

• 15317-58-5 1H-indole-3-carboxylic acid hydrazide 
• 41264-52-2 2-chloroethanimidic acid methyl ester 
• 79-11-8 chloroacetic acid 
• 942-24-5 3-methoxycarbonylindole 

Relevant articles and documents

Synthesis and antifungal activity of 3-(1,3,4-oxadiazol-5-yl)-indoles and 3-(1,3,4-oxadiazol-5-yl)methyl-indoles

On the basis of the principle of combination of active structural moieties, a modified and efficient synthetic method for three series of novel indole-based 1,3,4-oxadiazoles is described. Bioassays conducted at Syngenta showed that several of the synthesized compounds exhibit higher antifungal activity than pimprinine, the natural product which inspired this synthesis. Two main structural alterations were found to broaden the spectrum of biological activity in most cases. Compounds 3g, 6c, 6e, 6h, 9d, 9e, 9h and 9m (Fig. 1) were identified as the most active on the biological assays, and will be studied further.