851167-14-1

Basic information

• Product Name: 4-β-(4-fluorobenzyloxycarbonyl)amino-4'-tert-butyldimethylsilyloxy-4'-O-demethyl-4-desoxypodophyllotoxin
• Synonyms: 4-β-(4-fluorobenzyloxycarbonyl)amino-4'-tert-butyldimethylsilyloxy-4'-O-demethyl-4-desoxypodophyllotoxin
• CAS NO: 851167-14-1
• Molecular Weight: 665.788
• Mol File: 851167-14-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-β-(4-fluorobenzyloxycarbonyl)amino-4'-tert-butyldimethylsilyloxy-4'-O-demethyl-4-desoxypodophyllotoxin(CAS DataBase Reference)
• NIST Chemistry Reference: 4-β-(4-fluorobenzyloxycarbonyl)amino-4'-tert-butyldimethylsilyloxy-4'-O-demethyl-4-desoxypodophyllotoxin(851167-14-1)
• EPA Substance Registry System: 4-β-(4-fluorobenzyloxycarbonyl)amino-4'-tert-butyldimethylsilyloxy-4'-O-demethyl-4-desoxypodophyllotoxin(851167-14-1)

Safety Data

• Hazardous Substances Data: 851167-14-1(Hazardous Substances Data)

Upstream product

• 692755-45-6 4-β-amino-4'-tert-butyldimethylsilyloxy-4'-O-demethyl-4-desoxypodophyllotoxin 
• 851166-94-4 4-β-isocyanate-4'-tert-butyldimethylsilyloxy-4'-O-demethyl-4-desoxypodophyllotoxin 
• 459-56-3 4-fluorobenzylic alcohol 

Relevant articles and documents

Novel carbamate derivatives of 4-β-amino-4′-O-demethyl-4- desoxypodophyllotoxin as inhibitors of topoisomerase II: Synthesis and biological evaluation

A novel series of carbamate derivatives of 4-β-amino-4′-O- demethyl-4-desoxypodophyllotoxin were synthesized. Their effect on human DNA topoisomerase II and antiproliferative activity was evaluated. Compounds 4a-c, 4g, 4j and 4k are topoisomerase II poiso