851371-02-3Relevant articles and documents
Novel highly potent, structurally simple γ-trifluoromethyl γ-sulfone hydroxamate inhibitor of stromelysin-1 (MMP-3)
Sani, Monica,Candiani, Gabriele,Pecker, Fran?oise,Malpezzi, Luciana,Zanda, Matteo
, p. 2393 - 2396 (2005)
The γ-trifluoromethyl γ-sulfone hydroxamate 1 was synthesized both in racemic and enantiomerically pure forms by means of a thia-Michael reaction of p-methoxythiophenol on achiral and chiral 3,3,3-trifluorocrotonoyl Michael acceptors. The (R)-1 enantiomer