852123-16-1

Basic information

• Product Name: ((1S,2S,3S)-4-(4-(benzyloxy)benzo[d][1,3]dioxol-6-yl)-1-(5-bromo-4-methoxybenzo[d][1,3]dioxol-6-yl)-2,3-dimethylbutoxy)(tert-butyl)dimethylsilane
• Synonyms: ((1S,2S,3S)-4-(4-(benzyloxy)benzo[d][1,3]dioxol-6-yl)-1-(5-bromo-4-methoxybenzo[d][1,3]dioxol-6-yl)-2,3-dimethylbutoxy)(tert-butyl)dimethylsilane
• CAS NO: 852123-16-1
• Molecular Weight: 671.701
• Mol File: 852123-16-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: ((1S,2S,3S)-4-(4-(benzyloxy)benzo[d][1,3]dioxol-6-yl)-1-(5-bromo-4-methoxybenzo[d][1,3]dioxol-6-yl)-2,3-dimethylbutoxy)(tert-butyl)dimethylsilane(CAS DataBase Reference)
• NIST Chemistry Reference: ((1S,2S,3S)-4-(4-(benzyloxy)benzo[d][1,3]dioxol-6-yl)-1-(5-bromo-4-methoxybenzo[d][1,3]dioxol-6-yl)-2,3-dimethylbutoxy)(tert-butyl)dimethylsilane(852123-16-1)
• EPA Substance Registry System: ((1S,2S,3S)-4-(4-(benzyloxy)benzo[d][1,3]dioxol-6-yl)-1-(5-bromo-4-methoxybenzo[d][1,3]dioxol-6-yl)-2,3-dimethylbutoxy)(tert-butyl)dimethylsilane(852123-16-1)

Safety Data

• Hazardous Substances Data: 852123-16-1(Hazardous Substances Data)

Upstream product

• 852123-12-7 (1S,2S)-1-(5-bromo-4-methoxybenzo[d][1,3]dioxol-6-yl)-2,3-dimethylbut-3-en-1-ol 
• 852123-14-9 ((1S,2S)-1-(5-bromo-4-methoxybenzo[d][1,3]dioxol-6-yl)-2,3-dimethylbut-3-enyloxy)(tert-butyl)dimethylsilane 
• 81805-98-3 3-Hydroxy-4,5-(methylenedioxy)benzaldehyde 
• 795278-07-8 6-bromo-7-methoxybenzo[d][1,3] dioxole-5-carbaldehyde 
• 795278-08-9 6-bromo-7-hydroxybenzo[d][1,3]dioxole-5-carbaldehyde 
• 69739-34-0 t-butyldimethylsiyl triflate 
• 852123-08-1 4-benzyloxy-6-bromo-benzo[1,3]dioxole 

Downstream Products

• 181701-06-4 interiotherin A 

Relevant articles and documents

Asymmetric total synthesis of dibenzocyclooctadiene lignan natural products

Full details of the asymmetric total syntheses of the dibenzocyclooctadiene lignans interiotherin A, angeloylgomisin R, gomisin O, and gomisin E (epigomisin O) are presented. The syntheses were based on a unified synthetic strategy involving a novel crotylation using the Leighton auxiliary that occurred with excellent asymmetric induction (>98:2 enantiomeric ratio), a diastereoselective hydroboration/Suzuki-Miyaura coupling reaction sequence, and an atropdiastereoselective biarylcuprate coupling, both of which occurred with total (>20:1) stereocontrol. The syntheses were achieved in six to eight steps from simple aromatic precursors.