852686-98-7

Basic information

• Product Name: 2-bromo-N-(4-tert-butylphenyl)benzamide
• Synonyms: 2-bromo-N-(4-tert-butylphenyl)benzamide
• CAS NO: 852686-98-7
• Molecular Weight: 332.24
• Mol File: 852686-98-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-bromo-N-(4-tert-butylphenyl)benzamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-bromo-N-(4-tert-butylphenyl)benzamide(852686-98-7)
• EPA Substance Registry System: 2-bromo-N-(4-tert-butylphenyl)benzamide(852686-98-7)

Safety Data

• Hazardous Substances Data: 852686-98-7(Hazardous Substances Data)

Upstream product

• 769-92-6 4-tert-Butylaniline 
• 88-65-3 2-bromobenzoic-acid 
• 7154-66-7 2-bromobenzoic acid chloride 

Relevant articles and documents

Synthesis and antibacterial activity of 5-methylphenanthridium derivatives as FtsZ inhibitors

5-Methylphenanthridium derivatives were designed, synthesized and evaluated for their in vitro antibacterial activity and cell division inhibitory activity against various Gram-positive and -negative bacteria. Among them, compounds 5A2, 5B1, 5B2, 5B3, 5C1 and 5C2 displayed the best on-target antibacterial activity with an MIC value of 4?μg/mL against B. subtilis ATCC9372 and S. pyogenes PS, showing over 2-fold better activity than sanguinarine. The SARs showed that the 5-methylphenanthridium derivatives with the alkyl side chains at the 2-postion, especially the straight alkyl side chains exerted better on-target antibacterial activity.

Structural development studies of anti-hepatitis C virus agents with a phenanthridinone skeleton

A phenanthridinone skeleton was derived from our previous researches on thalidomide and retinoids as a multi-template for generation of anti-viral lead compounds. Structural development studies focusing on anti-hepatitis C virus activity afforded 5-butyl-2-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenanthridin-6(5H)-one (10) and 5-butylbenzo[b]phenanthridin-6(5H)-one (39), which showed EC50 values of approximately 3.7 and 3.2 μM, respectively.