853058-07-8

Basic information

• Product Name: CARBAMIC ACID, N-(6-AMINO-2-PYRIDINYL)-,PHENYLMETHYL ESTER
• Synonyms: CARBAMIC ACID, N-(6-AMINO-2-PYRIDINYL)-,PHENYLMETHYL ESTER;N-(6-Amino-2-pyridinyl)-carbamic acid phenylmethyl ester;benzyl (6-aminopyridin-2-yl)carbamate
• CAS NO: 853058-07-8
• Molecular Formula: C₁₃H₁₃N₃O₂
• Molecular Weight: 243.265
• Mol File: 853058-07-8.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: CARBAMIC ACID, N-(6-AMINO-2-PYRIDINYL)-,PHENYLMETHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: CARBAMIC ACID, N-(6-AMINO-2-PYRIDINYL)-,PHENYLMETHYL ESTER(853058-07-8)
• EPA Substance Registry System: CARBAMIC ACID, N-(6-AMINO-2-PYRIDINYL)-,PHENYLMETHYL ESTER(853058-07-8)

Safety Data

• Hazardous Substances Data: 853058-07-8(Hazardous Substances Data)

Usage

General Description

CARBAMIC ACID, N-(6-AMINO-2-PYRIDINYL)-, PHENYLMETHYL ESTER is a chemical compound that belongs to the class of carbamic acids and their derivatives. It is the phenylmethyl ester of N-(6-amino-2-pyridinyl)carbamic acid, which is a derivative of carbamic acid and contains an amino group on the 6-position of the pyridinyl ring. CARBAMIC ACID, N-(6-AMINO-2-PYRIDINYL)-,PHENYLMETHYL ESTER is commonly used in the pharmaceutical industry as a building block for the synthesis of various drugs and pharmaceuticals. It may also have potential applications in the field of agricultural chemistry and other industrial processes. However, as with any chemical compound, it is important to handle and use CARBAMIC ACID, N-(6-AMINO-2-PYRIDINYL)-, PHENYLMETHYL ESTER with caution and in accordance with proper safety protocols.

Upstream product

• 141-86-6 2.6-diaminopyridine 
• 501-53-1 benzyl chloroformate 

Downstream Products

• 853058-08-9 6-(6-benzyloxycarbonylamino-pyridin-2-ylcarbamoyl)-4-decyloxy-pyridine-2-carboxylic acid methyl ester 
• 853058-10-3 6-(6-benzyloxycarbonylamino-pyridin-2-ylcarbamoyl)-4-decyloxy-pyridine-2-carboxylic acid 
• 853058-11-4 6-(6-{[6-(6-benzyloxycarbonylamino-pyridin-2-ylcarbamoyl)-4-decyloxy-pyridine-2-carbonyl]-amino}-pyridin-2-ylcarbamoyl)-4-decyloxy-pyridine-2-carboxylic acid methyl ester 
• 853058-13-6 6-(6-{[6-(6-benzyloxycarbonylamino-pyridin-2-ylcarbamoyl)-4-decyloxy-pyridine-2-carbonyl]-amino}-pyridin-2-ylcarbamoyl)-4-decyloxy-pyridine-2-carboxylic acid 

Relevant articles and documents

APOPTOSIS SIGNAL-REGULATING KINASE 1 INHIBITORS AND METHODS OF USE THEREOF

The present invention discloses compounds of Formula (I), or pharmaceutically acceptable salts, ester, stereoisomer, tautomer, solvate, hydrate, or combination thereof: which inhibit the Apoptosis signal-regulating kinase 1 (ASK-1), which associated with autoimmune disorders, neurodegenerative disorders, inflammatory diseases, chronic kidney disease, cardiovascular disease. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject suffering from ASK-1 related disease. The invention also relates to methods of treating an ASK-1 related disease in a subject by administering a pharmaceutical composition comprising the compounds of the present invention. The present invention specifically relates to methods of treating ASK-1 associated with hepatic steatosis, including non-alcoholic fatty liver disease (NAFLD) and non-alcohol steatohepatitis disease (NASH).

Intramolecular versus intermolecular induction of helical handedness in pyridinedicarboxamide oligomers

A new convergent synthetic scheme has been developed to prepare oligoamides of 2,6-diaminopyridine and 4-decyloxy-2,6-pyridinedicarboxylic acid. These compounds adopt stable single helical conformations in solution. NMR and circular dichroism studies show