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854007-21-9

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854007-21-9 Usage

Description

(2S)-3-methyl-2-((2-thenoyl)-amino)butanoic acid is a chiral compound with the chemical formula C12H17NO3S. It is characterized by the presence of a thioester group and an amino group, which contribute to its potential biological activity and utility in organic synthesis and pharmaceutical research.

Uses

Used in Organic Synthesis:
(2S)-3-methyl-2-((2-thenoyl)-amino)butanoic acid is used as a building block in organic synthesis for the creation of various other compounds due to its versatile chemical structure and functional groups.
Used in Pharmaceutical Research:
(2S)-3-methyl-2-((2-thenoyl)-amino)butanoic acid is used as a precursor in pharmaceutical research for the development of new pharmaceutical agents, leveraging its thioester and amino groups for potential biological activity and medicinal applications.
Used in Chemical and Medicinal Industries:
(2S)-3-methyl-2-((2-thenoyl)-amino)butanoic acid is utilized across the chemical and medicinal industries for its potential applications in creating new compounds and pharmaceuticals, enhancing the development of innovative treatments and products.

Check Digit Verification of cas no

The CAS Registry Mumber 854007-21-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,5,4,0,0 and 7 respectively; the second part has 2 digits, 2 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 854007-21:
(8*8)+(7*5)+(6*4)+(5*0)+(4*0)+(3*7)+(2*2)+(1*1)=149
149 % 10 = 9
So 854007-21-9 is a valid CAS Registry Number.

854007-21-9Downstream Products

854007-21-9Relevant articles and documents

4-Sulfamoylphenylalkylamides as Inhibitors of Carbonic Anhydrases Expressed in Vibrio cholerae

Mancuso, Francesca,De Luca, Laura,Bucolo, Federica,Vrabel, Milan,Angeli, Andrea,Capasso, Clemente,Supuran, Claudiu T.,Gitto, Rosaria

, p. 3787 - 3794 (2021/10/20)

A current issue of antimicrobial therapy is the resistance to treatment with worldwide consequences. Thus, the identification of innovative targets is an intriguing challenge in the drug and development process aimed at newer antimicrobial agents. The state-of-art of anticholera therapy might comprise the reduction of the expression of cholera toxin, which could be reached through the inhibition of carbonic anhydrases expressed in Vibrio cholerae (VchCAα, VchCAβ, and VchCAγ). Therefore, we focused our interest on the exploitation of sulfonamides as VchCA inhibitors. We planned to design and synthesize new benzenesulfonamides based on our knowledge of the VchCA catalytic site. The synthesized compounds were tested thus collecting useful SAR information. From our investigation, we identified new potent VchCA inhibitors, some of them displayed high affinity toward VchCAγ class, for which few inhibitors are currently reported in literature. The best interesting VchCAγ inhibitor (S)-N-(1-oxo-1-((4-sulfamoylbenzyl)amino)propan-2-yl)furan-2-carboxamide (40) resulted more active and selective inhibitor when compared with acetazolamide (AAZ) as well as previously reported VchCA inhibitors.

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