854059-90-8

Basic information

• Product Name: 2-Benzothiazolecarboxaldehyde,5-methoxy-(5CI)
• Synonyms: 2-Benzothiazolecarboxaldehyde,5-methoxy-(5CI);5-methoxybenzo[d]thiazole-2-carbaldehyde;5-Methoxybenzothiazole-2-carboxaldehyde
• CAS NO: 854059-90-8
• Molecular Formula: C9H7NO2S
• Molecular Weight: 193.23
• Product Categories: BENZOTHIAZOLE
• Mol File: 854059-90-8.mol
• Article Data: 9

Chemical Properties

• Melting Point: 100-101 °C(Solv: ligroine (8032-32-4))
• Boiling Point: 145-160 °C(Press: 8 Torr)
• Appearance: /
• Density: 1.361±0.06 g/cm3(Predicted)
• PKA: -0.52±0.10(Predicted)
• CAS DataBase Reference: 2-Benzothiazolecarboxaldehyde,5-methoxy-(5CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Benzothiazolecarboxaldehyde,5-methoxy-(5CI)(854059-90-8)
• EPA Substance Registry System: 2-Benzothiazolecarboxaldehyde,5-methoxy-(5CI)(854059-90-8)

Safety Data

• Hazardous Substances Data: 854059-90-8(Hazardous Substances Data)

Upstream product

• 2941-69-7 5-methoxy-2-methylbenzo[d]thiazole 

Downstream Products

• 1204196-99-5 C₁₅H₁₇N₅OS 

Relevant articles and documents

Iodine-catalyzed oxidative annulation: Facile synthesis of pyrazolooxepinopyrazolones: Via methyl azaarene sp3C-H functionalization

An iodine-catalyzed methyl azaarene sp3 C-H functionalization has been developed for the synthesis of a seven-membered O-heterocyclic architecture containing three different heterocyclic aromatic hydrocarbons. This method can be applied to a wide range of substituted methyl azaarenes and diverse 2,4-dihydro-3H-pyrazol-3-ones, and brings about the efficient preparation of 2,9-dihydrooxepino[2,3-c:6,5-c′]dipyrazol-3(7H)-ones in high yields with the merits of low catalyst loading, good functional group tolerance and metal-free conditions.

Iodine-imine Synergistic Promoted Povarov-Type Multicomponent Reaction for the Synthesis of 2,2′-Biquinolines and Their Application to a Copper/Ligand Catalytic System

An efficient iodine-imine synergistic promoted Povarov-type multicomponent reaction was reported for the synthesis of a practical 2,2′-biquinoline scaffold. The tandem annulation has reconciled iodination, Kornblum oxidation, and Povarov aromatization, where the methyl group of the methyl azaarenes represents uniquely reactive input in the Povarov reaction. This method has broad substrate scope and mild conditions. Furthermore, these 2,2′-biquinoline derivatives had been directly used as bidentate ligands in metal-catalyzed reactions.

New method for synthesizing benzothiazole-2-formaldehyde and derivative thereof

The invention discloses a new synthetic method of benzothiazole-2-formaldehyde and a derivative thereof. The synthetic method comprises the following steps: dissolving 2-hydroxymethylbenzothiazole or substituent-2-hydroxymethylbenzothiazole in a certain amount of a solvent, adding an appropriate amount of manganese dioxide, and performing heating reaction for a period of time; and performing suction filtration, concentration and re-crystallization to obtain benzothiazole-2-formaldehyde and the derivative thereof. A reaction formula of the method disclosed by the invention is shown in the specification. The synthetic method disclosed by the invention has the advantages of being simple in operation, environment-friendly, low-price and easily-available in raw material, obviously improved in product quality, greatly improved in yield, and obviously reduced in reaction byproduct, and the like, and is suitable for large-scale production.