85514-25-6

Basic information

• Product Name: 11,12-dimethoxy-abieta-6,8,11,13-tetraen-20-oic acid methyl ester
• Synonyms: 11,12-dimethoxy-abieta-6,8,11,13-tetraen-20-oic acid methyl ester
• CAS NO: 85514-25-6
• Molecular Weight: 372.505
• Mol File: 85514-25-6.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 11,12-dimethoxy-abieta-6,8,11,13-tetraen-20-oic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 11,12-dimethoxy-abieta-6,8,11,13-tetraen-20-oic acid methyl ester(85514-25-6)
• EPA Substance Registry System: 11,12-dimethoxy-abieta-6,8,11,13-tetraen-20-oic acid methyl ester(85514-25-6)

Safety Data

• Hazardous Substances Data: 85514-25-6(Hazardous Substances Data)

Upstream product

• 5957-80-2 carnosol 
• 74-88-4 methyl iodide 

Downstream Products

• 27210-57-7 miltirone 

Relevant articles and documents

Oxidative C-ring opening of abietane diterpenes with ammonium cerium(IV) nitrate

The oxidation reaction of 11,12-di-O-methylcarnosol with ammonium cerium(IV) nitrate (CAN) gave an abietane diterpene with the C-ring opened and a diester function. The structure of this diester was established by spectroscopic analysis and by chemical means. The reaction of 11,12-di-O-dimethylgaldosol with CAN gave a similar result, yielding a δ-lactone which structure was established as 7-hydroxy-11,12-seco-8,13- abietadien-12,7:20,6β-dilacton-11-oic acid methyl ester by spectroscopic analysis and chemical means. These results could be useful to accede to other natural products like rosmic acid Georg Thieme Verlag Stuttgart.

A New Diterpene Lactone, Rosmadial, from Rosemary (Rosmarinus officinalis L.)

A new type of phenolic diterpene lactone, named rosmadial (1), was isolated from the leaves of rosemary (Rosmarinus officinalis L.), one of the herb spices belonging to the Family Labiatae.The structure has been determined to be 12-hydroxy-6,7-seco-11,10-epoxymethano-20-oxo-abieta-8,11,13-triene-6,7-dial by chemical and spectroscopic methods.The structure and stereochemistry were confirmed by synthesis from carnosol.

Antioxidative Effect of the Constituents of Rosemary (Rosmarinus officinalis L.) and Their Derivatives

Antioxidative activity was measured on extracts of rosemary (Rosmarinus officinalis L.), one of the herb spices belongs to the Family Labiatae, using different solvents.Strong activity was observed in the weakly acidic fraction of the n-hexane extract, which was further fractionated and purified to afford several active compounds.An odorless and colorless compound, named rosmanol, showed high antioxidative activity in both lard and linoleic acid, and particularly in lard, was about four times more active than synthetic antioxidants, such as BHT and BHA.Furthermore, the antioxidant activities of the derivatives of rosmanol and carnosol were measured by the ferric thiocyanate method and the TBA method, to observe the correlation between chemical structure and activity as an antioxidant.