857070-65-6 Usage
Description
1-((3-hydroxy-6-Methylpyridin-2-yl)Methyl)-2-((3-Morpholinopropyl)aMino)-1H-benzo[d]iMidazole-6-carbaldehyde is a complex organic chemical compound, classified as a benzimidazole derivative. It is characterized by the presence of a pyridine and morpholine functional group, along with an aldehyde group. This structural composition endows the compound with potential interactions with biomolecules, suggesting its possible utility in modulating biological processes. 1-((3-hydroxy-6-Methylpyridin-2-yl)Methyl)-2-((3-Morpholinopropyl)aMino)-1H-benzo[d]iMidazole-6-carbaldehyde is represented by the formula C20H24N4O3.
Uses
Used in Pharmaceutical Industry:
1-((3-hydroxy-6-Methylpyridin-2-yl)Methyl)-2-((3-Morpholinopropyl)aMino)-1H-benzo[d]iMidazole-6-carbaldehyde is used as a prospective pharmaceutical candidate due to its structural features that allow for interactions with biomolecules. 1-((3-hydroxy-6-Methylpyridin-2-yl)Methyl)-2-((3-Morpholinopropyl)aMino)-1H-benzo[d]iMidazole-6-carbaldehyde's potential to modulate biological processes makes it a candidate for further research and development in the medical field.
Used in Drug Development:
In the realm of drug development, 1-((3-hydroxy-6-Methylpyridin-2-yl)Methyl)-2-((3-Morpholinopropyl)aMino)-1H-benzo[d]iMidazole-6-carbaldehyde is utilized for its potential to contribute to the creation of novel therapeutic agents. 1-((3-hydroxy-6-Methylpyridin-2-yl)Methyl)-2-((3-Morpholinopropyl)aMino)-1H-benzo[d]iMidazole-6-carbaldehyde's unique structure may facilitate the design of new drugs targeting specific biological pathways or receptors, pending further investigation into its properties and applications.
Check Digit Verification of cas no
The CAS Registry Mumber 857070-65-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,5,7,0,7 and 0 respectively; the second part has 2 digits, 6 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 857070-65:
(8*8)+(7*5)+(6*7)+(5*0)+(4*7)+(3*0)+(2*6)+(1*5)=186
186 % 10 = 6
So 857070-65-6 is a valid CAS Registry Number.
857070-65-6Relevant articles and documents
Selection of a respiratory syncytial virus fusion inhibitor clinical candidate. 2. Discovery of a morpholinopropylaminobenzimidazole derivative (TMC353121)
Bonfanti, Jean-Fran?ois,Meyer, Christophe,Doublet, Frédéric,Fortin, Jér?me,Müller, Philippe,Queguiner, Laurence,Gevers, Tom,Janssens, Peggy,Szel, Heidi,Willebrords, Rudy,Timmerman, Philip,Wuyts, Koen,Van Remoortere, Pieter,Janssens, Frans,Wigerinck, Piet,Andries, Koen
, p. 875 - 896 (2008/09/19)
A preceding paper (Bonfanti et al. J. Med Chem. 2007, 50, 4572-4584) reported the optimization of the pharmacokinetic profile of substituted benzimidazoles by reducing their tissue retention. However, the modifications that were necessary to achieve this goal also led to a significant drop in anti-RSV activity. This paper describes a molecular modeling study followed by a lead optimization program that led to the recovery of the initial potent antiviral activity and the selection of TMC353121 as a clinical candidate.
MORPHOLINYL CONTAINING BENZIMIDAZOLES AS INHIBITORS OF RESPIRATORY SYNCYTIAL VIRUS REPLICATION
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Page/Page column 40-42, (2010/02/12)
The present invention concerns morpholinyl containing benzimidazoles having inhibitory activity on the replication of the respiratory syncytial virus and having the formula (I), a prodrug, N-oxide, addition salt, quaternary amine, metal complex or stereoc
