85803-63-0 Usage
Description
2-(4-METHYLPIPERAZIN-1-YL)BENZONITRILE, also known as MPB, is a chemical compound characterized by the presence of a piperazine ring and a benzonitrile group. It is widely recognized in the fields of medicinal chemistry and drug discovery for its role as a building block in the synthesis of pharmaceuticals. MPB's unique structure endows it with affinity for serotonin and adrenergic receptors, positioning it as a promising candidate for the development of novel drugs targeting central nervous system disorders.
Uses
Used in Pharmaceutical Synthesis:
2-(4-METHYLPIPERAZIN-1-YL)BENZONITRILE is used as a building block for the synthesis of pharmaceuticals due to its compatibility with various chemical reactions and its ability to contribute to the development of new drug candidates.
Used in Medicinal Chemistry Research:
MPB is used as a research chemical for exploring its interactions with serotonin and adrenergic receptors, which is crucial for understanding its potential therapeutic effects on central nervous system disorders.
Used in Drug Development for CNS Disorders:
2-(4-METHYLPIPERAZIN-1-YL)BENZONITRILE is used as a potential therapeutic agent for the treatment of central nervous system disorders such as depression, anxiety, and schizophrenia, owing to its demonstrated affinity for relevant receptors and its promising results in preclinical studies.
Used in Neuropharmacology and Neuroscience Research:
MPB is used as an important chemical probe for investigating the modulation of neuronal activity and behavior, contributing to the advancement of knowledge in neuropharmacology and neuroscience.
Used in Preclinical Studies:
2-(4-METHYLPIPERAZIN-1-YL)BENZONITRILE is used in preclinical studies to evaluate its efficacy and safety as a potential drug candidate for various central nervous system conditions, providing valuable data for further development and clinical trials.
Check Digit Verification of cas no
The CAS Registry Mumber 85803-63-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,5,8,0 and 3 respectively; the second part has 2 digits, 6 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 85803-63:
(7*8)+(6*5)+(5*8)+(4*0)+(3*3)+(2*6)+(1*3)=150
150 % 10 = 0
So 85803-63-0 is a valid CAS Registry Number.
InChI:InChI=1/C12H15N3/c1-14-6-8-15(9-7-14)12-5-3-2-4-11(12)10-13/h2-5H,6-9H2,1H3
85803-63-0Relevant articles and documents
Synthesis and biological evaluation of N-hydroxyphenylacrylamides and N-hydroxypyridin-2-ylacrylamides as novel histone deacetylase inhibitors
Thaler, Florian,Colombo, Andrea,Mai, Antonello,Amici, Raffaella,Bigogno, Chiara,Boggio, Roberto,Cappa, Anna,Carrara, Simone,Cataudella, Tiziana,Fusar, Fulvia,Gianti, Eleonora,Di Ventimiglia, Samuele Joppolo,Moroni, Maurizio,Munari, Davide,Pain, Gilles,Regalia, Nickolas,Sartori, Luca,Vultaggio, Stefania,Dondio, Giulio,Gagliardi, Stefania,Minucci, Saverio,Mercurio, Ciro,Varasi, Mario
supporting information; experimental part, p. 822 - 839 (2010/07/05)
The histone deacetylases (HDACs) are able to regulate gene expression, and histone deacetylase inhibitors (HDACi) emerged as a new class of agents in the treatment of cancer as well as other human disorders such as neurodegenerative diseases. In the prese
Method of inhibiting neoplastic cells with imidazoquinazoline derivatives
-
, (2008/06/13)
A method for inhibiting neoplasia, particularly cancerous and precancerous lesions by exposing the affected cells to imidazoquinazoline derivatives.
Synthesis and biological properties of thiophene ring analogues of mianserin.
Watthey,Gavin,Desai,Finn,Rodebaugh,Patt
, p. 1116 - 1122 (2007/10/02)
The synthesis of two thiophene-containing analogues of mianserin, i.e., 1,2,3,4,10,13b-hexahydro-2-methylpiperazino[1,2-a]thieno[2, 3-c][1]benzazepine (2), and the corresponding [3,2-c] isomer (12) is described. The key step in the synthesis is the nucleo
