85996-23-2Relevant articles and documents
Synthesis of C2-symmetric tris-thioethers via optically active mustards
Christoffers, Jens,R??ler, Ulrich
, p. 1779 - 1783 (2007/10/03)
Chiral dihydroxy thioethers derived from L-mandelic and L-lactic acid are activated with SOCl2, SOBr2 and by bis-trifluoroacetate formation to give optically active mustard gas analogues. These compounds serve as substrates for stereospecific nucleophilic substitution reactions with NaSEt and NaSPh to furnish C2-symmetric tris-thioethers with overall inversion of configuration.