862543-11-1

Basic information

• Product Name: 9-(2',3',5'-tri-O-benzoyl-β-L-ribofuranosyl)-2-chloro-6-(4-piperonylpiperazin-1-yl)purine
• Synonyms: 9-(2',3',5'-tri-O-benzoyl-β-L-ribofuranosyl)-2-chloro-6-(4-piperonylpiperazin-1-yl)purine
• CAS NO: 862543-11-1
• Molecular Weight: 817.255
• Mol File: 862543-11-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 9-(2',3',5'-tri-O-benzoyl-β-L-ribofuranosyl)-2-chloro-6-(4-piperonylpiperazin-1-yl)purine(CAS DataBase Reference)
• NIST Chemistry Reference: 9-(2',3',5'-tri-O-benzoyl-β-L-ribofuranosyl)-2-chloro-6-(4-piperonylpiperazin-1-yl)purine(862543-11-1)
• EPA Substance Registry System: 9-(2',3',5'-tri-O-benzoyl-β-L-ribofuranosyl)-2-chloro-6-(4-piperonylpiperazin-1-yl)purine(862543-11-1)

Safety Data

• Hazardous Substances Data: 862543-11-1(Hazardous Substances Data)

Upstream product

• 32231-06-4 1-Piperonylpiperazine 
• 162491-62-5 (2S,3R,4S)-2-(hydroxymethyl)-5-methoxyoxolane-3,4-diol 
• 5451-40-1 2,6 dichloropurine 
• 41546-21-8 L-ribose 
• 171866-28-7 1-O-methyl-2,3,5-tri-O-benzoyl-L-ribofuranose 
• 862543-05-3 2-chloro-6-(4-phenylpiperazin-1-yl)purine 
• 3080-30-6 1-O-acetyl-2,3,5-tri-O-benzoyl-β-L-ribofuranose 

Relevant articles and documents

A solid-phase approach to novel purine and nucleoside analogs

This paper describes a method for the preparation of purine analogs using the solid-phase approach. Nucleoside bases were constructed on Merrifield resin by sequential displacement of purine dichloride with amines, and after detachment, the purine analogs were condensed with d,l-ribofuranoside compounds by the Vorbrueggen method. Thereof, l-ribofuranoside was prepared from l-arabinose via the selective oxidation-reduction procedure of the 2-OH group. Some compounds exhibited moderate activity against HIV-1 in PBM cells.