862574-71-8

Basic information

• Product Name: 3-(2-CHLORO-6-FLUORO-PHENYL)-PROPIONALDEHYDE
• Synonyms: 3-(2-CHLORO-6-FLUORO-PHENYL)-PROPIONALDEHYDE;3-(2-chloro-6-fluorophenyl)propanal
• CAS NO: 862574-71-8
• Molecular Formula: C₉H₈ClFO
• Molecular Weight: 186.6106232
• Mol File: 862574-71-8.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 234.038 °C at 760 mmHg
• Flash Point: 95.343 °C
• Appearance: /
• Density: 1.226 g/cm³
• CAS DataBase Reference: 3-(2-CHLORO-6-FLUORO-PHENYL)-PROPIONALDEHYDE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(2-CHLORO-6-FLUORO-PHENYL)-PROPIONALDEHYDE(862574-71-8)
• EPA Substance Registry System: 3-(2-CHLORO-6-FLUORO-PHENYL)-PROPIONALDEHYDE(862574-71-8)

Safety Data

• Hazardous Substances Data: 862574-71-8(Hazardous Substances Data)

Upstream product

• 862574-70-7 3-(2-chloro-6-fluoro-phenyl)-propan-1-ol 

Downstream Products

• 862574-72-9 2-bromo-3-(2-chloro-6-fluoro-phenyl)-propionaldehyde 

Relevant articles and documents

MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS

The present invention relates to modulators of ATP-Binding Cassette ("ABC") transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator ("CFTR"), compositions thereof, and methods therewith. The present invention also relates to methods of treating ABC transporter mediated diseases using such modulators (I) or a pharmaceutically acceptable salt thereof, wherein: Ht is a 5-membered heteroaromatic ring containing 1-4 heteroatoms selected from O, S, N or NH, wherein said ring is optionally fused to a 6-membered monocyclic or 10-membered bicyclic carbocyclic or heterocyclic, aromatic or non-aromatic ring, wherein Ht is optionally substituted with w occurrences of -WRw, wherein w is 0-5; ring A is 3-7 membered monocyclic ring having 0-3 heteroatoms selected from O, S, N, or NH, wherein ring A is optionally substituted with q occurrences of QRQ; ring B is optionally fused to 5-6 membered carbocyclic or heterocyclic, aromatic or non-aromatic ring .