86303-23-3

Basic information

• Product Name: DEOXY-BIGCHAP
• Synonyms: DEOXY-BIGCHAP;BIG CHAP, DEOXY;N,N'-BIS(3-D-GLUCONAMIDOPROPYL)-DEOXY-CHOLAMIDE;N,N-BIS-(3-D-GLUCONAMIDOPROPYL)DEOXYCHOLAMIDE;N,N-BIS(3-GLUCONAMIDOPROPYL)DEOXYCHOLAMIDE;Deoxy-Bigchap(N,N-Bis[3-Glucoriamidopropyl]-Deoxycholamide;DeoxyBIGCHAP=BigCHAP,deoxy;(3a,5b,12a)-N,N-Bis[3-(D-gluconoylamino)propyl]-3,12-dihydroxycholan-24-amide
• CAS NO: 86303-23-3
• Molecular Formula: C42H75N3O15
• Molecular Weight: 862.06
• EINECS: 635-520-2
• Product Categories: Detergents
• Mol File: 86303-23-3.mol
• Article Data: 0

Chemical Properties

• Melting Point: 89-91°C
• Boiling Point: 1161.5 °C at 760 mmHg
• Flash Point: 656.2 °C
• Appearance: /
• Density: 1.337g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.589
• Storage Temp.: 2-8°C
• Solubility: DMSO (Slightly), Methanol (Slightly)
• Water Solubility: Soluble in water at 50mg/ml. Also soluble in DMSO or methanol.
• Stability: Moisture, Temperature Sensitive
• CAS DataBase Reference: DEOXY-BIGCHAP(CAS DataBase Reference)
• NIST Chemistry Reference: DEOXY-BIGCHAP(86303-23-3)
• EPA Substance Registry System: DEOXY-BIGCHAP(86303-23-3)

Safety Data

• Hazard Codes: Xi,T
• Statements: 36/37/38-48/20/22-22-46-45
• Safety Statements: 26-36-45-36/37/39-27-53
• WGK Germany: 3
• F: 10
• Hazardous Substances Data: 86303-23-3(Hazardous Substances Data)

Usage

Description

DEOXY-BIGCHAP, also known as N,N-Bis[3-(D-gluconamido)propyl]deoxycholamide, is a non-ionic detergent that is used for solubilizing cell membranes. It has properties comparable to CHAPS and CHAPSO but with reduced electrostatic interactions, making it suitable for ion exchange chromatography. DEOXY-BIGCHAP is easily removed by dialysis and has a low absorption in the UV region, making it a useful tool in biological systems and proteomic analysis.

Uses

Used in Biological Systems:
DEOXY-BIGCHAP is used as a surfactant and solubilizer for biological systems, aiding in the study and analysis of cellular components.
Used in Membrane Solubilization:
DEOXY-BIGCHAP is used for membrane solubilization, allowing for the isolation and analysis of membrane proteins and lipids.
Used in Proteomic Analysis:
DEOXY-BIGCHAP is used in proteomic analysis, enabling the solubilization of membrane proteins for further study and characterization.
Used in Ion Exchange Chromatography:
DEOXY-BIGCHAP is used as a nonionic detergent in ion exchange chromatography, providing reduced electrostatic interactions for improved separation and purification of proteins.

InChI:InChI=1/C42H75N3O15/c1-22(26-9-10-27-25-8-7-23-18-24(48)12-13-41(23,2)28(25)19-31(51)42(26,27)3)6-11-32(52)45(16-4-14-43-39(59)37(57)35(55)33(53)29(49)20-46)17-5-15-44-40(60)38(58)36(56)34(54)30(50)21-47/h22-31,33-38,46-51,53-58H,4-21H2,1-3H3,(H,43,59)(H,44,60)/t22-,23+,24-,25+,26+,27-,28+,29-,30-,31+,33-,34-,35+,36+,37-,38-,41+,42-/m1/s1