863870-77-3

Basic information

• Product Name: 3-CHLORO-2-IODOPHENYL N,N-DIETHYLCARBAMATE
• Synonyms: 3-CHLORO-2-IODOPHENYL N,N-DIETHYLCARBAMATE;3-CHLORO-2-IODOPHENYL N,N-DIETHYLCARBAMATE(WXG02757)
• CAS NO: 863870-77-3
• Molecular Formula: C₁₁H₁₃ClINO₂
• Molecular Weight: 353.58
• Product Categories: pharmacetical
• Mol File: 863870-77-3.mol
• Article Data: 12

Chemical Properties

• Boiling Point: 371.3°C at 760 mmHg
• Flash Point: 178.4°C
• Appearance: /
• Density: 1.622g/cm³
• Vapor Pressure: 1.04E-05mmHg at 25°C
• Refractive Index: 1.585
• CAS DataBase Reference: 3-CHLORO-2-IODOPHENYL N,N-DIETHYLCARBAMATE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-CHLORO-2-IODOPHENYL N,N-DIETHYLCARBAMATE(863870-77-3)
• EPA Substance Registry System: 3-CHLORO-2-IODOPHENYL N,N-DIETHYLCARBAMATE(863870-77-3)

Safety Data

• Hazardous Substances Data: 863870-77-3(Hazardous Substances Data)

Usage

InChI:InChI=1/C11H13ClINO2/c1-3-14(4-2)11(15)16-9-7-5-6-8(12)10(9)13/h5-7H,3-4H2,1-2H3

Upstream product

• 159390-33-7 3-chlorophenyl N,N-diethylcarbamate 
• 108-43-0 3-monochlorophenol 
• 88-10-8 N,N-diethylcarbamyl chloride 

Downstream Products

• 858854-82-7 3-chloro-2-iodo-phenol 
• 344562-15-8 4-chloro-2-phenylbenzo[b]furan 
• 220862-18-0 tert-butyl 2-(1-benzyl-2-ethyl-1H-indol-4-yloxy)acetate 
• 889675-08-5 tert-butyl 2-(3-(2-amino-2-oxoacetyl)-1-benzyl-2-ethyl-1H-indol-4-yloxy)acetate 
• 945470-01-9 1-chloro-2-iodo-3-(phenylmethoxy)benzene 
• 945470-02-0 tert-butyl 2-(3-chloro-2-iodophenoxy)acetate 
• 945470-03-1 3-chloro-2-iodo-1-triisopropylsilyloxybenzene 
• 945470-08-6 1-chloro-2-(1-hexynyl)-3-methoxybenzene 
• 945470-09-7 1-chloro-3-methoxy-2-(1-pentynyl)benzene 
• 945470-11-1 1-benzyloxy-3-chloro-2-(1-hexynyl)benzene 
• 945470-21-3 1-benzyl-2-butyl-4-methoxy-1H-indole 
• 945470-22-4 1-benzyl-2-propyl-4-methoxy-1H-indole 
• 945470-24-6 1-benzyl-4-benzyloxy-2-butyl-1H-indole 
• 945470-30-4 4-benzyloxy-2-butyl-1H-indole 

Relevant articles and documents

KINASE INHIBITOR

[Problem] To provide a novel PIM-3 inhibitor and a novel cancer therapeutic drug, in particular, a therapeutic drug for pancreatic cancer. [Solution] A PIM-3 kinase inhibitor comprising a compound represented by general formula (I) or a pharmacologically acceptable salt, hydrate or solvate thereof.

Combined directed ortho metalation-halogen dance (HD) synthetic strategies. HD-anionic ortho fries rearrangement and double HD sequences

A general and efficient directed ortho metalation (DoM)-halogen dance (HD)-electrophile quench sequence for the synthesis of trisubstituted pyridyl O-carbamates is described. A second HD sequence furnishes highly functionalized tetrasubstituted pyridines.

Synthesis of 4-functionalized-1H-indoles from 2,3-dihalophenols

A new synthesis of 4-halo-1H-indoles has been developed from easily available 2,3-dihalophenol derivatives. The key steps are Smiles rearrangement and a one-pot or stepwise Sonogashira coupling/NaOH-mediated cyclization. Subsequent functionalization allows access to a wide variety of 2,4- or 2,3,4-regioselectively functionalized indoles.