864754-38-1Relevant articles and documents
Stereocomplementary asymmetric bioreduction of boron-containing ketones mediated by alcohol dehydrogenases
Barcellos, Thiago,Tauber, Katharina,Kroutil, Wolfgang,Andrade, Leandro H.
experimental part, p. 1772 - 1777 (2012/01/03)
Optically active boron-containing alcohols were prepared via the stereoselective reduction of the corresponding carbonyl compounds by alcohol dehydrogenases. Depending on the substrate, both (R)-alcohols and (S)-alcohols were obtained with excellent enantioselectivity (up to >99% ee) employing either ADH-A or LB-ADH.