86523-75-3Relevant articles and documents
Synthesis and antiallergic activity of N-(pyridin-2-yl)-3-(piperazin-1-yl) propanamides
Courant,Leblois,Le Baut,Venco,Panconi
, p. 821 - 824 (2007/10/02)
A series of 6 new N-(pyridin-2-yl)-3-(piperazin-1-yl)propanamides were synthesized from the corresponding N-pyridinylpropenamides to determine potential antiallergic activity as assayed in vivo by the passive cutaneous anaphylaxis test. The IC50 of compound 12 after oral administration was comparable to that of oxatomide.