86883-41-2Relevant articles and documents
Synthesis of Glycosyl Fluorides by Photochemical Fluorination with Sulfur(VI) Hexafluoride
Bannykh, Anton,Khomutnyk, Yaroslav,Kim, Sungjin,Nagorny, Pavel
, p. 190 - 194 (2021)
This study describes a new convenient method for the photocatalytic generation of glycosyl fluorides using sulfur(VI) hexafluoride as an inexpensive and safe fluorinating agent and 4,4′-dimethoxybenzophenone as a readily available organic photocatalyst. This mild method was employed to generate 16 different glycosyl fluorides, including the substrates with acid and base labile functionalities, in yields of 43%-97%, and it was applied in continuous flow to accomplish fluorination on an 7.7 g scale and 93% yield.
SIMPLE SYNTHESIS OF GLYCOSYL FLUORIDES
Hayashi, Masahiko,Hashimoto, Shun-ichi,Noyori, Ryoji
, p. 1747 - 1750 (2007/10/02)
Treatment of 1-unprotected or -O-acetylated sugar derivatives with a hydrogen fluoride-pyridine mixture affords the corresponding 1-fluoro derivatives in high yields.