869109-01-3

Basic information

• Product Name: Methyl 4-(6-fluoropyridin-2-yloxy)benzenecarboxylate
• Synonyms: Methyl 4-(6-fluoropyridin-2-yloxy)benzenecarboxylate
• CAS NO: 869109-01-3
• Molecular Weight: 247.226
• Mol File: 869109-01-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Methyl 4-(6-fluoropyridin-2-yloxy)benzenecarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: Methyl 4-(6-fluoropyridin-2-yloxy)benzenecarboxylate(869109-01-3)
• EPA Substance Registry System: Methyl 4-(6-fluoropyridin-2-yloxy)benzenecarboxylate(869109-01-3)

Safety Data

• Hazardous Substances Data: 869109-01-3(Hazardous Substances Data)

Upstream product

• 1513-65-1 2,6-difluoro pyridine 
• 99-76-3 methyl 4-hydroxylbenzoate 
• 20885-12-5 2-chloro-6-fluoropyridine 

Downstream Products

• 1247779-45-8 C₁₂H₁₀FNO₂ 

Relevant articles and documents

Heterobiaryl and heterobiaryl ether derived M5 positive allosteric modulators

This Letter describes a chemical lead optimization campaign directed at VU0238429, the first M5-preferring positive allosteric modulator (PAM), discovered through analog work around VU0119498, a pan Gq mAChR M1, M3, M5 PAM. An iterative parallel synthesis approach was employed to incorporate basic heterocycles to improve physiochemical properties.