869376-63-6 Usage
Description
CB-25 is a stable analog of Δ9-tetrahydrocannabinol (THC) and anandamide (AEA), characterized by its high affinity for both central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors. It functions as an inverse agonist for the CB1 receptor, as demonstrated in a cyclic AMP (cAMP) functional assay.
Uses
Used in Pharmaceutical Industry:
CB-25 is used as a stable anandamide analog CB1 inverse agonist for the development of potential therapeutic agents targeting the endocannabinoid system. Its high affinity for CB1 and CB2 receptors makes it a promising candidate for research and drug development in various medical applications.
Check Digit Verification of cas no
The CAS Registry Mumber 869376-63-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,6,9,3,7 and 6 respectively; the second part has 2 digits, 6 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 869376-63:
(8*8)+(7*6)+(6*9)+(5*3)+(4*7)+(3*6)+(2*6)+(1*3)=236
236 % 10 = 6
So 869376-63-6 is a valid CAS Registry Number.
869376-63-6Relevant articles and documents
POTENT AND SELECTIVE LIGANDS OF CANNABINOID RECEPTORS
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Page/Page column 4, (2009/03/07)
The present invention relates to high affinity compounds, able to bind CB1 and CB2 endocannabinoid receptors. The compounds of the invention find particular application as agents for pain therapy and/or anti-inflammatory and/or anti-
Design, synthesis, and binding studies of new potent ligands of cannabinoid receptors
Brizzi, Antonella,Brizzi, Vittorio,Cascio, Maria Grazia,Bisogno, Tiziana,Sirianni, Rossella,Marzo, Vincenzo Di
, p. 7343 - 7350 (2007/10/03)
Despite their different chemical structures, Δ9- tetrahydrocannabinol (THC) and anandamide (AEA) have common pharmacological properties. This study was aimed at finding new cannabinoid receptor ligands that overcome the instability of AEA and i
