869586-85-6Relevant articles and documents
Design and synthesis of substituted nicotinamides as inhibitors of soluble epoxide hydrolase
Taylor, Steven J.,Soleymanzadeh, Fariba,Eldrup, Anne B.,Farrow, Neil A.,Muegge, Ingo,Kukulka, Alison,Kabcenell, Alisa K.,Lombaert, Stephane De
scheme or table, p. 5864 - 5868 (2010/08/03)
A series of potent nicotinamide inhibitors of soluble epoxides hydrolase (sEH) is disclosed. This series was designed using structure-based deconstruction and a combination of two HTS hit series, resulting in hybrid analogs that retained the optimal poten
SUBSTITUTED PYRIDINEAMIDE COMPOUNDS USEFUL AS SOLUBLE EPOXIDE HYDROLASE INHIBITORS
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Page/Page column 69, (2008/06/13)
Disclosed are compounds active against soluble epoxide hydrolase (sEH), compositions thereof and methods of using and making same.