87-47-8

Basic information

• Product Name: Pyrolan.
• Synonyms: (5-methyl-2-phenyl-pyrazol-3-yl) N,N-dimethylcarbamate;ENT-17588;G-22008;Geigy G-22008;N,N-Dimethylcarbamic acid 3-methyl-1-phenyl-1H-pyrazol-5-yl;Pyralan;N,N-dimethylcarbamic acid (5-methyl-2-phenyl-pyrazol-3-yl) ester;PyrolanR
• CAS NO: 87-47-8
• Molecular Formula: C₁₃H₁₅N₃O₂
• Molecular Weight: 245.31
• Mol File: 87-47-8.mol
• Article Data: 0

Chemical Properties

• Melting Point: 50°
• Boiling Point: bp0.2 160-162°
• Flash Point: 178.7°C
• Appearance: crystalline solid
• Density: 1.1477 (rough estimate)
• Vapor Pressure: 9.97E-06mmHg at 25°C
• Refractive Index: 1.5600 (estimate)
• Water Solubility: 1.996g/L(temperature not stated)
• Stability: Stability Incompatible with strong oxidizing agents.
• CAS DataBase Reference: Pyrolan.(CAS DataBase Reference)
• NIST Chemistry Reference: Pyrolan.(87-47-8)
• EPA Substance Registry System: Pyrolan.(87-47-8)

Safety Data

• RIDADR: 2757
• HazardClass: 6.1(b)
• PackingGroup: III
• Hazardous Substances Data: 87-47-8(Hazardous Substances Data)

Usage

Description

Pyrolan is a derivative of 3-Methyl-1-phenyl-2-pyrazolin-5-one (E335000), characterized as a crystalline solid that is soluble in water and fats. It is recognized for its ability to inhibit disease activity in rheumatoid arthritis, making it a valuable compound in the medical field.

Uses

Used in Pharmaceutical Industry:
Pyrolan is used as an anti-inflammatory agent for the treatment of rheumatoid arthritis. It helps in reducing inflammation and pain associated with the condition by inhibiting the disease activity.
Used in Agricultural Industry:
Pyrolan is used as an insecticide to control and eliminate pests that can damage crops and affect agricultural productivity. Its effectiveness in this application contributes to ensuring a healthy and sustainable crop yield.

Air & Water Reactions

Water soluble.

Reactivity Profile

Pyrolan. is a carbamate ester. Carbamates are chemically similar to, but more reactive than amides. Like amides they form polymers such as polyurethane resins. Carbamates are incompatible with strong acids and bases, and especially incompatible with strong reducing agents such as hydrides. Flammable gaseous hydrogen is produced by the combination of active metals or nitrides with carbamates. Strongly oxidizing acids, peroxides, and hydroperoxides are incompatible with carbamates.

Hazard

Toxic by ingestion. Cholinesterase inhibitor.

Health Hazard

ACUTE/CHRONIC HAZARDS: Pyrolan. is a reversible CHOLINESTERASE INHIBITOR. When heated to decomposition it emits toxic fumes of nitrogen oxides.

Fire Hazard

Flash point data for Pyrolan. are not available; however, Pyrolan. is probably combustible.

InChI:InChI=1/C13H15N3O2/c1-10-9-12(18-13(17)15(2)3)16(14-10)11-7-5-4-6-8-11/h4-9H,1-3H3

Upstream product

• 19735-89-8 3-methyl-1-phenylpyrazolin-5(4H)-one