870680-39-0Relevant articles and documents
Microwave-assisted synthesis of some novel azoles and azolopyrimidines as antimicrobial agents
Gomha, Sobhi M.,Farghaly, Thoraya A.,Mabkhot, Yahia Nasser,Zayed, Mohie E. M.,Mohamed, Amany M. G.
, (2017)
In this study, new derivatives of pyrazole, isoxazole, pyrazolylthiazole, and azolopyrimidine having a thiophene ring were synthesized under microwave irradiation. Their pharmacological activity toward bacteria and fungi inhibition was screened and compared to the references Chloramphenicol and Trimethoprim/sulphamethoxazole. The antimicrobial results of the investigated compounds revealed promising results and some derivatives have activities similar to the references used.
Synthesis and studies on antidepressant and anticonvulsant activities of some 3-(2-thienyl)pyrazoline derivatives
Ozdemir, Zuhal,Kandilci, H. Burak,Gumusel, Bulent,Calis, Unsal,Bilgin, A. Altan
experimental part, p. 701 - 707 (2009/04/06)
In this study, the synthesis of twelve 3-(2-thienyl)pyrazoline derivatives are described. The structures of all compounds were confirmed by UV, IR, 1H-NMR, mass spectral data, and microanalyses. In the pharmacological studies, antidepressant an