87186-38-7

Basic information

• Product Name: N-(2-Chloro-4-methoxyphenyl)aniline
• Synonyms: N-(2-Chloro-4-methoxyphenyl)aniline
• CAS NO: 87186-38-7
• Molecular Weight: 0
• Mol File: 87186-38-7.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: N-(2-Chloro-4-methoxyphenyl)aniline(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2-Chloro-4-methoxyphenyl)aniline(87186-38-7)
• EPA Substance Registry System: N-(2-Chloro-4-methoxyphenyl)aniline(87186-38-7)

Safety Data

• Hazardous Substances Data: 87186-38-7(Hazardous Substances Data)

Upstream product

• 62-53-3 aniline 
• 36404-30-5 3,4-dichloroanisole 

Relevant articles and documents

Palladium C-N bond formation catalysed by air-stable robust polydentate ferrocenylphosphines: A comparative study for the efficient and selective coupling of aniline derivatives to dichloroarene

The arylation of aniline derivatives with dichloroarenes under a low palladium content (below the currently used 5 to 10 mol%) was studied using nine different ferrocenylphosphine ligands, including the easily accessible 1,1′-bis(diphenylphosphino)ferrocene, DPPF. The electron-enriched air-stable tridentate ferrocenylpolyphosphine 1,2-bis(diphenylphosphino)- 1′-(diisopropylphosphino)-4-tert-butylferrocene, L5, employed in 2 mol% in combination with 1 mol% [PdCl(η3-C3H 5)]2 allows an efficient and selective coupling, while such demanding substrates currently induce chloroarene homocoupling and/or dehalogenation processes. The scope and limitation of the optimized system are explored, with a focus on electron-poor fluoroanilines (deactivated nucleophiles) and electron-rich methylated and methoxylated dichlorobenzenes (deactivated electrophiles). The Royal Society of Chemistry 2014.