873221-58-0

Basic information

• Product Name: HEXAHYDROPYRIDAZINE HYDROCHLORIDE
• Synonyms: HEXAHYDROPYRIDAZINE HYDROCHLORIDE
• CAS NO: 873221-58-0
• Molecular Formula: C4H11ClN2
• Molecular Weight: 122.6
• Mol File: 873221-58-0.mol
• Article Data: 20

Chemical Properties

• Appearance: /
• CAS DataBase Reference: HEXAHYDROPYRIDAZINE HYDROCHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: HEXAHYDROPYRIDAZINE HYDROCHLORIDE(873221-58-0)
• EPA Substance Registry System: HEXAHYDROPYRIDAZINE HYDROCHLORIDE(873221-58-0)

Safety Data

• Hazardous Substances Data: 873221-58-0(Hazardous Substances Data)

Upstream product

• 189807-28-1 tetrahydropyridazine-1,2-dicarbaldehyde 
• 110-52-1 1,4-dibromo-butane 
• 340256-13-5 tert-butyl 2-[(tert-butyl)oxycarbonyl]perhydropyridazine-1-carboxylate 
• 154972-37-9 tert-butyl tetrahydropyridazine-1(2H)-carboxylate 
• 289-80-5 1,2-diazine 
• 68387-96-2 N,N'-diisobutyrylhexahydropyridazine 

Downstream Products

• 1160943-52-1 trans-cinnamaldehyde dimethylacetal 
• 1160943-43-0 C₁₃H₁₇N₂⁽¹⁺⁾*ClH 
• 1160943-48-5 C₁₃H₁₇N₂⁽¹⁺⁾*ClH 
• 1609108-32-8 N-(6-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}hexanoyl)-L-valyl-N⁵-carbamoyl-N-(4-{[(tenahydropyridazin-1(2H)-ylcarbonyl)oxy]methyl}phenyl)-L-ornithinamide 

Relevant articles and documents

Preparation method of hexahydropyridazine dihydrochloride

The invention relates to a preparation method of hexahydropyridazine dihydrochloride, which comprises the following steps: reacting formic acid with hydrazine hydrate to generate N,N'-diformylhydrazine; then reacting the N,N'-diformylhydrazine with 1,4-dibromobutane under the alkaline condition to generate tetrahydropyridazine-1,2-diformaldehyde; and finally reacting the tetrahydropyridazine-1,2-diformaldehyde with hydrochloric acid to generate the hexahydropyridazine dihydrochloride. Compared with the prior art, the method provided by the invention has the advantages of easily available and cheap raw materials, mild reaction, simple operation, low requirements on reaction equipment, and easy industrialization.

Substituted Pyrazalones

The invention is related to compounds of formula (I) as antagonists of the TGFβ family type I receptors, Alk5 and/or AIk 4, compositions and methods of use. The compounds of formula (I) can be employed in the prevention and/or treatment of diseases such a

Biginelli reactions catalyzed by hydrazine type organocatalyst

Pyrazolidine dihydrochloride can be used in the acceleration of Biginelli reactions between urea, ethyl acetoacetate and various aldehydes to provide DHPMs in good to excellent yields.