87353-15-9

Basic information

• Product Name: tetrabutylammonium benzylglutarate
• CAS NO: 87353-15-9
• Molecular Weight: 463.701
• Mol File: 87353-15-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: tetrabutylammonium benzylglutarate(CAS DataBase Reference)
• NIST Chemistry Reference: tetrabutylammonium benzylglutarate(87353-15-9)
• EPA Substance Registry System: tetrabutylammonium benzylglutarate(87353-15-9)

Safety Data

• Hazardous Substances Data: 87353-15-9(Hazardous Substances Data)

Upstream product

• 108-55-4 glutaric anhydride, 
• 54322-10-0 glutaric acid monobenzyl ester 
• 32503-27-8 tetra(n-butyl)ammonium hydrogensulfate 
• 100-51-6 benzyl alcohol 

Downstream Products

• 87343-61-1 benzyl chloromethyl pentanedioate 
• 87343-26-8 <<5-(benzyloxy)glutaryl>oxy>methyl penicillanate sulfone 

Relevant articles and documents

Orally effective acid prodrugs of the β-lactamase inhibitor sulbactam

Sulbactam (1) is a β-lactamase inhibitor with limited oral bioavailability. Lipophilic double-ester prodrug sulbactam pivoxil (2) significantly improves the oral absorption of sulbactam, as does the mutual prodrug double ester sultamicillin (3). We have found that double-ester prodrugs of sulbactam terminating in a carboxyl group (8) also were effective oral-delivery vehicles in rats. Carboxyl-terminated double esters have several potential advantages over their nonionizable lipophilic counterparts, including water solubility, crystallinity, choice of salts for dosage forms, and formation of innocuous byproducts on hydrolysis.