874219-17-7 Usage
General Description
2-(morpholin-4-ylcarbonyl)benzenboronic acid is a boronic acid derivative with a morpholine group attached to the benzenboronic acid core. It is commonly used as a building block in organic synthesis and pharmaceutical research. 2-(MORPHOLIN-4-YLCARBONYL)BENZENEBORONIC ACID is known for its ability to form stable complexes with various biological substrates, making it useful in the development of new drugs and chemical probes. The morpholine group also imparts favorable solubility and reactivity properties, making it a versatile tool for the modification of molecules in drug discovery and medicinal chemistry. Additionally, the boronic acid functionality enables it to participate in Suzuki-Miyaura coupling reactions, further expanding its utility in organic synthesis.
Check Digit Verification of cas no
The CAS Registry Mumber 874219-17-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,7,4,2,1 and 9 respectively; the second part has 2 digits, 1 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 874219-17:
(8*8)+(7*7)+(6*4)+(5*2)+(4*1)+(3*9)+(2*1)+(1*7)=187
187 % 10 = 7
So 874219-17-7 is a valid CAS Registry Number.
InChI:InChI=1/C11H14BNO4/c14-11(13-5-7-17-8-6-13)9-3-1-2-4-10(9)12(15)16/h1-4,15-16H,5-8H2
874219-17-7Relevant articles and documents
Scope of the palladium-catalyzed aryl borylation utilizing bis-boronic acid
Molander, Gary A.,Trice, Sarah L. J.,Kennedy, Steven M.,Dreher, Spencer D.,Tudge, Matthew T.
supporting information; experimental part, p. 11667 - 11673 (2012/09/05)
The Suzuki-Miyaura reaction has become one of the more useful tools for synthetic organic chemists. Until recently, there did not exist a direct way to make the most important component in the coupling reaction, namely the boronic acid. Current methods to make boronic acids often employ harsh or wasteful reagents to prepare boronic acid derivatives and require additional steps to afford the desired boronic acid. The scope of the previously reported palladium-catalyzed, direct boronic acid synthesis is unveiled, which includes a wide array of synthetically useful aryl electrophiles. It makes use of the newly available second generation Buchwald XPhos preformed palladium catalyst and bis-boronic acid. For ease of isolation and to preserve the often sensitive C-B bond, all boronic acids were readily converted to their more stable trifluoroborate counterparts.
