874291-00-6

Basic information

• Product Name: 4-[(ETHYLCARBAMOYL)AMINO]BENZENEBORONIC ACID, PINACOL ESTER 98%4-(3-ETHYLUREIDO)BENZENEBORONIC ACID, PINACOL ESTER
• Synonyms: 4-[(ETHYLCARBAMOYL)AMINO]BENZENEBORONIC ACID, PINACOL ESTER 98%4-(3-ETHYLUREIDO)BENZENEBORONIC ACID, PINACOL ESTER;4-[(ETHYLCARBAMOYL)AMINO]BENZENEBORONIC ACID, PINACOL ESTER;4-(3-ETHYLUREIDO)BENZENEBORONIC ACID, PINACOL ESTER;4-(3-ETHYLUREIDO)PHENYLBORONIC ACID, PINACOL ESTER;1-ETHYL-3-[4-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PHENYL]UREA;4-[(Ethylcarbamoyl)amino]benzeneboronic acid, pinacol ester 98%;4-[(Ethylcarbamoyl)amino]benzeneboronicacid,pinacolester98%;4-[(ETHYLCARBAMOYL)AMINO]BENZENEBORONIC ACID, PINACOL ESTER 98%4-(3-ETHYLUREIDO)BENZENEBORONIC ACID, PINACOL ESTER
• CAS NO: 874291-00-6
• Molecular Formula: C₁₅H₂₃BN₂O₃
• Molecular Weight: 290.17
• EINECS: 200-589-5
• Product Categories: blocks;BoronicAcids
• Mol File: 874291-00-6.mol
• Article Data: 4

Chemical Properties

• Melting Point: 194-196
• Boiling Point: 392℃
• Flash Point: 191℃
• Appearance: /
• Density: 1.09
• Vapor Pressure: 2.3E-06mmHg at 25°C
• Refractive Index: 1.519
• Storage Temp.: Keep Cold
• CAS DataBase Reference: 4-[(ETHYLCARBAMOYL)AMINO]BENZENEBORONIC ACID, PINACOL ESTER 98%4-(3-ETHYLUREIDO)BENZENEBORONIC ACID, PINACOL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 4-[(ETHYLCARBAMOYL)AMINO]BENZENEBORONIC ACID, PINACOL ESTER 98%4-(3-ETHYLUREIDO)BENZENEBORONIC ACID, PINACOL ESTER(874291-00-6)
• EPA Substance Registry System: 4-[(ETHYLCARBAMOYL)AMINO]BENZENEBORONIC ACID, PINACOL ESTER 98%4-(3-ETHYLUREIDO)BENZENEBORONIC ACID, PINACOL ESTER(874291-00-6)

Safety Data

• Hazard Codes: Xi
• Hazardous Substances Data: 874291-00-6(Hazardous Substances Data)

Usage

General Description

4-[(ethylcarbamoyl)amino]benzenboronic acid, pinacol ester and 4-(3-ethylureido)benzenboronic acid, pinacol ester are both organic compounds used in chemical research and pharmaceutical synthesis. They are utilized as reagents and intermediates in the production of various pharmaceuticals, agrochemicals, and advanced materials. These chemicals are commonly used in the synthesis of bioactive molecules and are known for their potential in drug discovery and development. They are both available in high purity forms, with a concentration of 98%, making them suitable for use in advanced research and development projects.

InChI:InChI=1/C15H23BN2O3/c1-6-17-13(19)18-12-9-7-11(8-10-12)16-20-14(2,3)15(4,5)21-16/h7-10H,6H2,1-5H3,(H2,17,18,19)

Upstream product

• 75-04-7 ethylamine 
• 106-40-1 4-bromo-aniline 
• 82745-18-4 1-(4-bromophenyl)-3-ethylurea 
• 25015-63-8 4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane 

Downstream Products

• 1101799-29-4 3-Ethyl-1-[4-[4-[(3S)-3-methylmorpholin-4-yl]-6-(1-methylsulfonylcyclopropyl)pyrimidin-2-yl]phenyl]urea 
• 1207360-75-5 1-ethyl-3-(4-(4-morpholino-8-oxo-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-2-yl)phenyl)urea 
• 1207360-92-6 tert-butyl 2-(4-(3-ethylureido)phenyl)-4-(pyridin-4-yl)-5,6-dihydropyrido[3,4-d]pyrimidine-7(8H)-carboxylate 
• 1207360-96-0 1-(4-(4-(3,3-dimethylmorpholino)-7-(2-methoxyethyl)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-2-yl)phenyl)-3-ethylurea 
• 1207365-96-5 tert-butyl 2-(4-(3-ethylureido)phenyl)-4-morpholino-5H-pyrrolo[3,4-d]pyrimidine-6(7H)-carboxylate 
• 1227062-24-9 C₁₈H₂₁ClN₆O₂ 
• 1260088-54-7 1-ethyl-3-(4-(4-morpholino-7,8-dihydro-6H-pyrano[3,2-d]pyrimidin-2-yl)phenyl)urea 
• 1260088-69-4 (S)-1-(4-(7,7-dimethyl-4-(3-methylmorpholino)-5,7-dihydrofuro[3,4-d]pyrimidin-2-yl)phenyl)-3-ethylurea 
• 1260089-82-4 (+/-)-1-(4-(7-allyl-7-methyl-4-morpholino-5,7-dihydrofuro[3,4-d]pyrimidin-2-yl)phenyl)-3-ethylurea 
• 1260090-14-9 1-(4-((S)-7-allyl-7-methyl-4-((S)-3-methylmorpholino)-5,7-dihydrofuro[3,4-d]pyrimidin-2-yl)phenyl)-3-ethylurea 
• 1260090-16-1 1-(4-((R)-7-allyl-7-methyl-4-((S)-3-methylmorpholino)-5,7-dihydrofuro[3,4-d]pyrimidin-2-yl)phenyl)-3-ethylurea 
• 1260090-94-5 1-(4-(7,7-dimethyl-4-morpholino-5-oxo-5,7-dihydrofuro[3,4-d]pyrimidin-2-yl)phenyl)-3-ethylurea 
• 1262443-62-8 1-ethyl-3-(4-(4'-morpholino-5'H-spiro-[cyclopropane-1,7'-furo[3,4-d]pyrimidine]-2'-yl)phenyl)urea 
• 1285499-86-6 1-ethyl-3-(4-(7-methyl-6-morpholino-7H-purin-2-yl)phenyl)urea 

Relevant articles and documents

Pyrido-pyrimidines, its preparation and use

The invention discloses pyridopyrimidine compounds with a general formula (I), wherein Ar is aryl or heteroaryl; R1 is hydrogen, halogen, amino, heterocyclic group, alkyl, aminoalkyl, heterocyclic alkyl, aryl, heteroaryl, cyano, alkenyl or alkynyl; R2 is

As the PI3K/mTOR inhibitor tricyclic compound, its preparation and use

The invention discloses a tricyclic compound as a PI3K/mTOR inhibitor. The tricyclic compound is a compound with the general formula (I) in the specification, wherein Ar is selected from aryl or heteroaryl; X, Y and Z are independently selected from O, CR2R3 and NR4 respectively; Q is selected from O, CR2R3 and NR4 or does not exists; R1 represents C1-C6 alkyl; n is selected from integers from 0 to 4; when n is more than or equal to 2, two R1 and a morpholine cycle can be combined into a combined cycle, a bridge cycle or a spiral cycle; R2 and R3 are selected from hydrogen and C1-C6 alkyl; R4 is selected from hydrogen, C1-C6 alkyl, C3-C7 cycloalkyl, heterocyclic radical, acyl and sulfonyl. The invention further discloses a perpetration method of the compound with the general formula (I) as well as a pharmaceutical composition and application of the compound with the general formula (I).