87488-84-4

Basic information

• Product Name: 1-(2-BROMOPHENYL)-1H-PYRAZOLE
• Synonyms: BUTTPARK 98\50-72;1-(2-BROMOPHENYL)-1H-PYRAZOLE;1-(2-Bromophenyl)-1H-pyrazole 97%;1-(2-Bromophenyl)pyrazole;1H-Pyrazole, 1-(2-bromophenyl)-;1-(2-Bromophenyl)-1H-pyrazole97%
• CAS NO: 87488-84-4
• Molecular Formula: C9H7BrN2
• Molecular Weight: 223.07
• Mol File: 87488-84-4.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 296.6 °C at 760 mmHg
• Flash Point: 133.2 °C
• Appearance: /
• Density: 1.5 g/cm³
• Vapor Pressure: 0.00251mmHg at 25°C
• Refractive Index: 1.64
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• PKA: -0.31±0.10(Predicted)
• CAS DataBase Reference: 1-(2-BROMOPHENYL)-1H-PYRAZOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2-BROMOPHENYL)-1H-PYRAZOLE(87488-84-4)
• EPA Substance Registry System: 1-(2-BROMOPHENYL)-1H-PYRAZOLE(87488-84-4)

Safety Data

• Hazardous Substances Data: 87488-84-4(Hazardous Substances Data)

Usage

General Description

1-(2-Bromophenyl)-1H-pyrazole is a chemical compound with the molecular formula C9H6BrN2. It is categorized as a pyrazole, which is a class of organic compounds with a five-membered aromatic ring, containing two nitrogen atoms and three carbon atoms. The exact properties such as boiling point, melting point and density can vary depending on the specific structure and bonding. This chemical shows promise in various fields such as pharmaceuticals and agrochemicals for its potential biochemical properties, although its specific use and toxicity is not widely documented and would require further detailed study.

InChI:InChI=1/C9H7BrN2/c10-8-4-1-2-5-9(8)12-7-3-6-11-12/h1-7H

Upstream product

• 102-52-3 malonaldehydebis(dimethylacetal) 
• 16732-66-4 2-bromophenylhydrazine 
• 288-13-1 NH-pyrazole 
• 1072-85-1 o-fluorobromobenzene 
• 108-86-1 bromobenzene 

Relevant articles and documents

Rhodium-Catalyzed Dealkenylative Arylation of Alkenes with Arylboronic Compounds

The C?C bond formation reaction represents a fundamental and important transformation in synthetic chemistry, and exploring new types of C?C bond formation reactions is recognized as appealing, yet challenging. Herein, we disclose the first example of rhodium-catalyzed dealkenylative arylation of alkenes with arylboronic compounds, thereby providing an unconventional access to bi(hetero)aryls with excellent chemoselectivity. In this method, C(aryl)?C(alkenyl) and C(alkenyl)?C(alkenyl) bonds in various alkenes and 1,3-dienes can be cleaved via a hydrometalation and followed by β-carbon elimination pathway for Suzuki–Miyaura reactions. Furthermore, a series of novel organic fluorescent molecules with excellent photophysical properties has been efficiently constructed with this protocol.

Electrophotocatalysis with a Trisaminocyclopropenium Radical Dication

Visible-light photocatalysis and electrocatalysis are two powerful strategies for the promotion of chemical reactions. Here, these two modalities are combined in an electrophotocatalytic oxidation platform. This chemistry employs a trisaminocyclopropenium (TAC) ion catalyst, which is electrochemically oxidized to form a cyclopropenium radical dication intermediate. The radical dication undergoes photoexcitation with visible light to produce an excited-state species with oxidizing power (3.33 V vs. SCE) sufficient to oxidize benzene and halogenated benzenes via single-electron transfer (SET), resulting in C?H/N?H coupling with azoles. A rationale for the strongly oxidizing behavior of the photoexcited species is provided, while the stability of the catalyst is rationalized by a particular conformation of the cis-2,6-dimethylpiperidine moieties.

Catalyst-free N-arylation using unactivated fluorobenzenes

Caught in a 'SNAr'e: A one-step, high-yielding, catalyst-free method is described for N-arylation of azoles and indoles from unactivated monofluorobenzenes. This SNAr reaction tolerates a wide range of substituents and can also generate halogenated N-aryl products. The reaction can also be performed simultaneously with or subsequent to a copper- or palladium-catalyzed cross-coupling reaction in the same pot. Copyright