874895-86-0

Basic information

• Product Name: Oxazole, 4,5-dihydro-4,4-dimethyl-2-(1-phenylcyclohexyl)-
• CAS NO: 874895-86-0
• Molecular Formula: C17H23NO
• Molecular Weight: 257.376
• Mol File: 874895-86-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Oxazole, 4,5-dihydro-4,4-dimethyl-2-(1-phenylcyclohexyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Oxazole, 4,5-dihydro-4,4-dimethyl-2-(1-phenylcyclohexyl)-(874895-86-0)
• EPA Substance Registry System: Oxazole, 4,5-dihydro-4,4-dimethyl-2-(1-phenylcyclohexyl)-(874895-86-0)

Safety Data

• Hazardous Substances Data: 874895-86-0(Hazardous Substances Data)

Upstream product

• 1135-67-7 1-phenyl-cyclohexanecarboxylic acid 
• 2890-42-8 1-phenylcyclohexylcarbonyl chloride 
• 124-68-5 2-Amino-2-methyl-1-propanol 

Downstream Products

• 1039038-35-1 4,5-dihydro-2-(1-(2-iodophenyl)cyclohexyl)-4,4-dimethyloxazole 

Relevant articles and documents

Remote C-H bond functionalization reveals the distance-dependent isotope effect

Iodination of remote aryl C-H bonds has been achieved using palladium acetate as the catalyst and iodoacetate (IOAc) as the oxidant. Systematic kinetic isotope studies imply a mechanistic regime shift as the number of bonds separating the directing heteroatom and the target C-H bond increases. Both isotope and electronic effects observed in remote C-H bond activation are consistent with an electrophilic palladation pathway in which the initial palladation is slower than the C-H bond cleavage.