87583-89-9 Usage
Description
(1S,2S)-N,N'-Dimethyl-1,2-cyclohexanediamine is a chiral diamine compound with a cyclohexane ring and two methyl groups attached to the nitrogen atoms. It is characterized by its stereochemistry, with both the 1 and 2 positions being in the S configuration.
Uses
Used in Pharmaceutical Industry:
(1S,2S)-N,N'-Dimethyl-1,2-cyclohexanediamine is used as a key intermediate in the synthesis of 6-substituted 1-oxoindanoyl isoleucine conjugates, which have potential applications in drug development and medicinal chemistry.
Used in Agricultural Research:
It is employed in modeling studies with the coi1-jaz co-receptor complex of lima bean, which helps in understanding the molecular mechanisms of plant defense responses and can contribute to the development of more effective crop protection strategies.
Used in Organic Chemistry:
(1S,2S)-N,N'-Dimethyl-1,2-cyclohexanediamine is used as a starting material for the synthesis of α-diazophosphonic acid derivatives, which are versatile reagents in O-H and N-H insertion reactions, enabling the formation of various organic compounds.
Used in Inorganic Chemistry:
It serves as a starting material for the synthesis of α-chloro-α-alkylphosphonic acids, which are important intermediates in the preparation of organophosphorus compounds with potential applications in various fields, such as agrochemicals and pharmaceuticals.
Used in Materials Science:
(1S,2S)-N,N'-Dimethyl-1,2-cyclohexanediamine is used to prepare C2 symmetrical diamine enantiomers of C60, which exhibit chirospectrosopic properties. These enantiomers have potential applications in the development of new materials with unique optical and electronic properties.
Check Digit Verification of cas no
The CAS Registry Mumber 87583-89-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,7,5,8 and 3 respectively; the second part has 2 digits, 8 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 87583-89:
(7*8)+(6*7)+(5*5)+(4*8)+(3*3)+(2*8)+(1*9)=189
189 % 10 = 9
So 87583-89-9 is a valid CAS Registry Number.
87583-89-9Relevant articles and documents
Method for synthesizing trans-cyclohexanedimethanamine
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Paragraph 0011; 0012; 0013; 0014; 0015; 0016; 0017; 0018, (2017/08/28)
The invention discloses a method for synthesizing trans-cyclohexanedimethanamine, comprising steps of reacting cyclohexene oxide and methylamine aqueous solution under the catalysis of boric acid, and then adding sulfuric acid, dewatering to form an ester, ring-closing under alkaline conditions, adding methylamine aqueous solution and boric acid for hermetic reaction, and distilling to obtain trans-cyclohexanedimethanamine. The synthetic process is simple to perform, provides facilitated isolation and purification and high yield and product purity, and is suitable for batch production.
On the two-ligand catalytic asymmetric deprotonation of N-Boc pyrrolidine: Probing the effect of the stoichiometric ligand
Bilke, Julia L.,O'Brien, Peter
, p. 6452 - 6454 (2008/12/21)
(Chemical Equation Presented) To map out the stoichiometric ligand requirements in the two-ligand catalytic asymmetric deprotonation of N-Boc pyrrolidine, 24 different ligands have been evaluated; the highest enantioselectivity (90:10 er) was obtained by using s-BuLi in the presence of 0.3 equiv of (-)-sparteine and 1.3 equiv of a cyclohexanediamine-derived ligand.
The copper-catalyzed N-arylation of indoles
Antilla, Jon C.,Klapars, Artis,Buchwald, Stephen L.
, p. 11684 - 11688 (2007/10/03)
A general method for the N-arylation of indoles using catalysts derived from Cul and trans-1,2-cyclohexanediamine (1a), trans-N,N′-dimethyl-1,2-cyclohexanediamine (2a), or N,N′-dimethyl-ethylenediamine (3) is reported. N-Arylindoles can be produced in high yield from the coupling of an aryl iodide or aryl bromide with a variety of indoles.
