87691-88-1 Usage
Description
3-Piperazinyl-1,2-benzisothiazole hydrochloride is an organic compound that serves as a crucial building block in the synthesis of various pharmaceuticals, particularly in the preparation of Ziprasidone, a medication used for the treatment of psychiatric disorders.
Uses
Used in Pharmaceutical Industry:
3-Piperazinyl-1,2-benzisothiazole hydrochloride is used as a key intermediate in the synthesis of Ziprasidone (Z485000), a combined serotonin (5HT2) and dopamine (D2) receptor antagonist. It plays a vital role in the development of this antipsychotic medication, which is effective in managing symptoms of schizophrenia and bipolar disorder.
Additionally, due to its unique chemical structure and properties, 3-Piperazinyl-1,2-benzisothiazole hydrochloride may also be utilized in the research and development of other potential therapeutic agents targeting similar receptors or pathways in the treatment of various neurological and psychiatric conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 87691-88-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,7,6,9 and 1 respectively; the second part has 2 digits, 8 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 87691-88:
(7*8)+(6*7)+(5*6)+(4*9)+(3*1)+(2*8)+(1*8)=191
191 % 10 = 1
So 87691-88-1 is a valid CAS Registry Number.
InChI:InChI=1/C11H13N3S.ClH/c1-2-4-10-9(3-1)11(13-15-10)14-7-5-12-6-8-14;/h1-4,12H,5-8H2;1H
87691-88-1Relevant articles and documents
Processes and intermediates for preparing 3-(1-piperazinyl)-1,2-benzisothiazole
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, (2008/06/13)
The present invention relates to processes for the preparation of 3-(1-piperazinyl)-1,2-benzoisothiazole or its pharmaceutically acceptable salt and to novel intermediates used in the process.
PRO-DRUGS OF 5-(2-(4-(1,2-BENZISOTHIAZOL-3-YL)-1-PIPERAZINYL)ETHYL)-6-CHLORO-1,3-DIHYDRO-2H-INDOL-2-ONE
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, (2008/06/13)
The present invention relates to a pro-drug of ziprasidone or pharmaceutically acceptable salts thereof, processes for its preparation, and pharmaceutical compositions and methods of treatment comprising said pro-drug.
1,2,4-TRIAZOL-3-ONE ANTIDEPRESSANTS
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, (2008/06/13)
Phenoxyalkyl substituted-1,2,4-triazolones having anti-depressant properties typified by 2-3-4-(3-chlorophenyl)-1-piperazinyl!propyl!-5-ethyl-4-(2-phenoxyethyl)-2H-1,2, 4-triazol-3(4H)-one are disclosed.