876953-54-7

Basic information

• Product Name: L-Phenylalanine, (4S)-1-[(1,1-dimethylethoxy)carbonyl]-4-(methylthio)-L-prolyl-L-leucyl-, methyl ester
• CAS NO: 876953-54-7
• Molecular Formula: C27H41N3O6S
• Molecular Weight: 535.705
• Mol File: 876953-54-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: L-Phenylalanine, (4S)-1-[(1,1-dimethylethoxy)carbonyl]-4-(methylthio)-L-prolyl-L-leucyl-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: L-Phenylalanine, (4S)-1-[(1,1-dimethylethoxy)carbonyl]-4-(methylthio)-L-prolyl-L-leucyl-, methyl ester(876953-54-7)
• EPA Substance Registry System: L-Phenylalanine, (4S)-1-[(1,1-dimethylethoxy)carbonyl]-4-(methylthio)-L-prolyl-L-leucyl-, methyl ester(876953-54-7)

Safety Data

• Hazardous Substances Data: 876953-54-7(Hazardous Substances Data)

Upstream product

• 188109-89-9 (2S,4S)-4-methylsulfanyl-pyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester 
• 6461-07-0 methyl (S)-2-[(S)-2-amino-4-methylpentanamido]-3-phenylpropanoate hydrochloride 
• 51-35-4 4R-4-hydroxyproline 
• 211299-16-0 1-(tert-butyl) 2-methyl 4-(acetylthio)pyrrolidine-1,2-dicarboxylate 
• 84520-67-2 (2S,4R)-4-(methylsulfonyloxy)pyrrolidine-1,2-dicarboxylic acid 1-tert-butylester-2-methylester 
• 74844-91-0 1-tert-butyl 2-methyl (2S,4R)-4-hydroxy-1,2-pyrrolidinedicarboxylate 
• 40216-83-9 L-4-hydroxyproline methyl ester hydrochloride 
• 15136-32-0 (N-(tert-butoxycarbonyl)-L-leucinyl)-L-phenylalanine methyl ester 
• 24424-99-5 di-tert-butyl dicarbonate 

Relevant articles and documents

Chemotactic peptides: fMLF-OMe analogues incorporating proline-methionine chimeras as N-terminal residue

The new fMLF analogues 1-4, incorporating chimeric S-proline-methionine residues (namely the homochiral cis-4(S)-methylthio-(S)-proline (10) and the heterochiral trans-4(R)-methylthio-(S)-proline) (17) in place of the native S-methionine, have been prepared; their solution conformation and activity as agonists or antagonists of formylpeptide receptors have been studied. In addition to peptides 1-4, which maintain the Met γ-thiomethyl-ether function, the analogues Boc-PLF-OMe (18) and For-PLF-OMe (19) devoid, as compared with 1-4, of position 1 side chain, have been synthesized and their activity examined.