87700-65-0

Basic information

• Product Name: 4-bromonaphthalene-1-carbonyl chloride
• Synonyms: 4-bromonaphthalene-1-carbonyl chloride;1-Naphthalenecarbonyl chloride, 4-bromo-;4-Bromo-1-naphthalenecarbonyl chloride;4-Bromo-1-naphthoyl chloride
• CAS NO: 87700-65-0
• Molecular Formula: C11H6BrClO
• Molecular Weight: 269.524
• Mol File: 87700-65-0.mol
• Article Data: 11

Chemical Properties

• Boiling Point: 358.4°C at 760 mmHg
• Flash Point: 170.6°C
• Appearance: /
• Density: 1.622g/cm³
• Vapor Pressure: 2.55E-05mmHg at 25°C
• Refractive Index: 1.669
• CAS DataBase Reference: 4-bromonaphthalene-1-carbonyl chloride(CAS DataBase Reference)
• NIST Chemistry Reference: 4-bromonaphthalene-1-carbonyl chloride(87700-65-0)
• EPA Substance Registry System: 4-bromonaphthalene-1-carbonyl chloride(87700-65-0)

Safety Data

• Hazardous Substances Data: 87700-65-0(Hazardous Substances Data)

Usage

InChI:InChI=1/C11H6BrClO/c12-10-6-5-9(11(13)14)7-3-1-2-4-8(7)10/h1-6H

Upstream product

• 16650-55-8 4-bromonaphthalene-1-carboxylic acid 
• 83-53-4 1,4-dibromonaphthalene 
• 90-11-9 1-Bromonaphthalene 
• 35615-97-5 4-bromo-naphthalene-1-carboxylic acid methyl ester 
• 46258-62-2 1-(4-bromonaphthalen-1-yl)ethanone 
• 2298-07-9 4-Bromo-1-naphthylamine 
• 92616-49-4 4-bromonaphthalene-1-carbonitrile 

Downstream Products

• 87700-83-2 4-Bromo-naphthalene-1-carboxylic acid phenylamide 
• 35615-97-5 4-bromo-naphthalene-1-carboxylic acid methyl ester 
• 3839-19-8 4-cyano-1-naphthoic acid 
• 1366067-59-5 (4-bromo-1-naphthalenyl)(1-pentyl-1H-indol-3-yl)methanone 
• 1366067-63-1 JWH-394 
• 929000-22-6 tert-butyl 4-bromonaphthalene-1-carboxylate 
• 664364-43-6 (4-cyanonaphthalen-1-yl)boronic acid 
• 92616-49-4 4-bromonaphthalene-1-carbonitrile 

Relevant articles and documents

Process Development, Manufacture, and Understanding of the Atropisomerism and Polymorphism of Verinurad

The manufacturing route toward verinurad, an amphoteric, class II atropisomer that readily forms solvates, has proven to be highly complex. This previously required the isolation of intermediates with challenging physical properties and the application of cryogenic processes. New processes were designed and optimized, enabling the manufacture of 113 kg of verinurad in its desired polymorphic form. An interdisciplinary approach involving the synthesis, high-throughput experimentation, analytical chemistry, crystallization science, in silico modeling, and engineering was employed. Kinetic measurement of enantiomerically enriched verinurad salts confirmed that racemization occurred within the clearance time frame, thus mitigating safety concerns associated with inherent axial chirality in verinurad.

Palladium-catalyzed directing group-assisted C8-triflation of naphthalenes

The transition-metal-catalyzed direct triflation of naphthyl amides and naphthyl ketones has been accomplished for the first time. Benzophenone (BP) was found to be a suitable ligand for the cross-coupling reactions. Density functional theory (DFT) calculations revealed that excessive amounts of HOTf inhibit the reductive elimination of the C-F bond to realize the unusual reductive elimination of the C-OTf bond.

NAPHTHYL- OR ISOQUINOLINYL-SUBSTITUTED ISOTHIAZOLINE COMPOUNDS

The present invention relates to naphthyl-or isoquinolinyl-substituted isothiazoline compounds of formula (I) wherein the variables are as defined in the claims and description. The compounds are useful for combating or controlling invertebrate pests, in