877264-48-7

Basic information

• Product Name: Benzo[b]thiophen-6-yl trifluoromethanesulfonate
• Synonyms: Benzo[b]thiophen-6-yl trifluoromethanesulfonate;1,1,1-Trifluoromethanesulfonic acid benzo[b]thien-6-yl ester
• CAS NO: 877264-48-7
• Molecular Formula: C9H5F3O3S2
• Molecular Weight: 282.262
• Mol File: 877264-48-7.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 344.9±42.0 °C(Predicted)
• Appearance: /
• Density: 1.617±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• CAS DataBase Reference: Benzo[b]thiophen-6-yl trifluoromethanesulfonate(CAS DataBase Reference)
• NIST Chemistry Reference: Benzo[b]thiophen-6-yl trifluoromethanesulfonate(877264-48-7)
• EPA Substance Registry System: Benzo[b]thiophen-6-yl trifluoromethanesulfonate(877264-48-7)

Safety Data

• Hazardous Substances Data: 877264-48-7(Hazardous Substances Data)

Usage

General Description

Benzo[b]thiophen-6-yl trifluoromethanesulfonate is a chemical compound with the molecular formula C8H5F3O3S and a molecular weight of 250.19 g/mol. It is a white to off-white solid that is used as a reagent in organic synthesis. Benzo[b]thiophen-6-yl trifluoromethanesulfonate is often utilized in the preparation of various pharmaceuticals and agrochemicals. It is a trifluoromethanesulfonate ester, a class of compounds known for their use as nucleophiles in organic chemistry reactions. Benzo[b]thiophen-6-yl trifluoromethanesulfonate is considered to be a useful and versatile building block in the synthesis of complex organic molecules. However, it should be handled with care due to its potential hazards if mishandled.

Upstream product

• 19301-39-4 1-benzothiophen-6-ol 
• 358-23-6 trifluoromethylsulfonic anhydride 

Downstream Products

• 29813-41-0 6-acetylbenzothiophene 

Relevant articles and documents

Aryl- and heteroaryl-substituted tetrahydroisoquinolines and use thereof to block reuptake of norepinephrine, dopamine, and serotonin

The compounds of the present invention are represented by the chemical structure found in Formula (I): wherein: the carbon atom designated * is in the R or S configuration; and X is a fused bicyclic carbocycle or heterocycle selected from the group consisting of benzofuranyl, benzo[b]thiophenyl, benzoisothiazolyl, benzoisoxazolyl, indazolyl, indolyl, isoindolyl, indolizinyl, benzoimidazolyl, benzooxazolyl, benzothiazolyl, benzotriazolyl, imidazo[1,2-a]pyridinyl, pyrazolo[1,5-a]pyridinyl, [1,2,4]triazolo[4,3-a]pyridinyl, thieno[2,3-b]pyridinyl, thieno[3,2-b]pyridinyl, 1H-pyrrolo[2,3-b]pyridinyl, indenyl, indanyl, dihydrobenzocycloheptenyl, tetrahydrobenzocycloheptenyl, dihydrobenzothiophenyl, dihydrobenzofuranyl, indolinyl, naphthyl, tetrahydronaphthyl, quinolinyl, isoquinolinyl, 4H-quinolizinyl, 9aH-quinolizinyl, quinazolinyl, cinnolinyl, phthalazinyl, quinoxalinyl, benzo[1,2,3]triazinyl, benzo[1,2,4]triazinyl, 2H-chromenyl, 4H-chromenyl, and a fused bicyclic carbocycle or fused bicyclic heterocycle optionally substituted with substituents (1 to 4 in number) as defined in R14; with R1, R2, R3, R4, R5, R6, R7, R8, and R14 defined herein.