878-86-4 Usage
Description
6-chloro-3-methyl-5-nitropyrimidine-2,4(1H,3H)-dione is a chemical compound with the molecular formula C6H4ClN3O4. It is an organic compound that belongs to the class of nitropyrimidines. This chemical is a yellow to orange crystalline solid and is mainly used as an intermediate in the synthesis of various pharmaceuticals and agrochemicals. It is also known for its antimicrobial properties and can be used in the manufacturing of antibacterial agents. Additionally, it has potential application in the field of organic synthesis and medicinal chemistry due to its unique structure and properties.
Uses
Used in Pharmaceutical Industry:
6-chloro-3-methyl-5-nitropyrimidine-2,4(1H,3H)-dione is used as an intermediate in the synthesis of various pharmaceuticals for its ability to be incorporated into the molecular structure of different drugs.
Used in Agrochemical Industry:
6-chloro-3-methyl-5-nitropyrimidine-2,4(1H,3H)-dione is used as an intermediate in the synthesis of various agrochemicals for its potential to be part of the formulation of pesticides or other agricultural products.
Used in Antimicrobial Applications:
6-chloro-3-methyl-5-nitropyrimidine-2,4(1H,3H)-dione is used as an antimicrobial agent for its ability to inhibit the growth of bacteria, making it suitable for the manufacturing of antibacterial agents.
Used in Organic Synthesis:
6-chloro-3-methyl-5-nitropyrimidine-2,4(1H,3H)-dione is used in organic synthesis for its unique structure and properties, allowing it to be a component in the creation of new organic compounds.
Used in Medicinal Chemistry:
6-chloro-3-methyl-5-nitropyrimidine-2,4(1H,3H)-dione is used in medicinal chemistry for its potential to contribute to the development of new drugs and therapeutic agents due to its distinctive chemical characteristics.
Check Digit Verification of cas no
The CAS Registry Mumber 878-86-4 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 8,7 and 8 respectively; the second part has 2 digits, 8 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 878-86:
(5*8)+(4*7)+(3*8)+(2*8)+(1*6)=114
114 % 10 = 4
So 878-86-4 is a valid CAS Registry Number.
878-86-4Relevant articles and documents
Synthesis and quantitative structure-activity relationship (QSAR) analysis of some novel oxadiazolo[3,4-d]pyrimidine nucleosides derivatives as antiviral agents
Xu, Xiaojuan,Wang, Jun,Yao, Qizheng
, p. 241 - 244 (2015/02/19)
We have synthesized a series of 4H,6H-[1,2,5]oxadiazolo[3,4-d]pyrimidine-5,7-dione 1-oxide nucleoside and their anti-vesicular stomatitis virus (VSV) activities in Wish cell were also investigated in vitro. It was found that most compounds showed obvious anti-VSV activities and compound 9 with ribofuranoside improved the anti-VSV activity by approximately 10 times and 18 times compared to didanosine (DDI) and acyclovir, respectively. A quantitative structure-activity relationship (QSAR) study of these compounds as well as previous reported oxadiazolo[3,4-d]pyrimidine nucleoside derivatives indicated that compounds with high activity should have small values of log P(o/w), vsurf-G and a large log S value. These findings and results provide a base for further investigations.
PURINES AND PYRIMIDINES AND CONDENSED SYSTEMS BASED ON THEM. 2. SYNTHESIS OF 1-METHYL-9-AMINOXANTHINE AND 9-AMINOTHEOPHYLLINE
Kuz'menko, V. V.,Kuz'menko, T. A.,Aleksandrov, G. G.,Pozharskii, A. F.,Gulevskaya, A. V.
, p. 690 - 697 (2007/10/02)
The previously unknown 9-aminotheophylline and 1-methyl-9-aminoxanthine were synthesized from 3-methyl-5-amino-6-hydrazinouracil.In the case of 1-methyl-9-aminoxanthine an x-ray diffraction study of an N-amino derivative of an NH heterocycle was made for the first time.