88-09-5 Usage
Description
2-Ethylbutyric acid is a clear, colorless liquid with a rancid, oily-fruity, and acidulous odor. It is miscible in alcohol and ether, sparingly soluble in water, and is obtained by chemical synthesis.
Uses
Used in Environmental Analysis:
2-Ethylbutyric acid is used as an internal standard for determining volatile fatty acids (VFAs) in wastewater from constructed wetlands.
Used in Food Analysis:
2-Ethylbutyric acid is used in the determination of both free and fatty acids in milk and milk products by the HPLC method with direct derivatization.
Used in Flavoring:
2-Ethylbutyric acid is used as a flavoring agent, providing an acidic, fruity, tropical taste with a creamy aftertaste. It has a taste threshold value of 35 ppm.
Used in Chemical Synthesis:
2-Ethylbutyric acid is used as an intermediate for the synthesis of drugs, dyes, and chemicals.
Used in Ester Formation:
2-Ethylbutyric acid is used in the formation of esters.
Occurrence:
2-Ethylbutyric acid is found in various fruits, bread, and cheeses, including guava, wheaten bread, Parmesan, blue, cheddar, provolone, Romano, and goat cheeses, apple, banana, grape, melon, papaya, peach, and pineapple.
Aroma Threshold Values:
The detection threshold for 2-Ethylbutyric acid is between 15 to 600 ppb.
Preparation
By catalytic oxidation of diethylacetaldehyde or by decarboxylation of diethylmalonic acid.
Safety Profile
Moderately toxic by
ingestion and skin contact. An irritant to
skin and mucous membranes. A severe eye
irritant. See also ESTERS. Narcotic in high
concentrations. Flammable liquid. To fight
fire, use CO2, dry chemical, alcohol foam.
When heated to decomposition it emits
acrid smoke and fumes.
Check Digit Verification of cas no
The CAS Registry Mumber 88-09-5 includes 5 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 2 digits, 8 and 8 respectively; the second part has 2 digits, 0 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 88-09:
(4*8)+(3*8)+(2*0)+(1*9)=65
65 % 10 = 5
So 88-09-5 is a valid CAS Registry Number.
InChI:InChI=1/C6H12O2/c1-3-5(4-2)6(7)8/h5H,3-4H2,1-2H3,(H,7,8)/p-1
88-09-5Relevant articles and documents
Ruthenium-catalysed hydroxycarbonylation of olefins
Dühren, Ricarda,Kucmierczyk, Peter,Jackstell, Ralf,Franke, Robert,Beller, Matthias
, p. 2026 - 2030 (2021/04/09)
State-of-the-art catalyst systems for hydroxy- and alkoxycarbonylations of olefins make use of palladium complexes. In this work, we report a complementary ruthenium-catalysed hydroxycarbonylation of olefins applying an inexpensive Ru-precursor (Ru3(CO)12) and PCy3as a ligand. Crucial for the success of this transformation is the use of hexafluoroisopropanol (HFIP) as the solvent in the presence of an acid co-catalyst (PTSA). Overall, moderate to good yields are obtained using aliphatic olefins including the industrially relevant substrate di-isobutene. This atom-efficient catalytic transformation provides straightforward access to various carboxylic acids from unfunctionalized olefins.
COMPOUNDS AND USES
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Page/Page column 21, (2019/11/04)
The invention relates to novel compounds (I), the use of compounds in eliciting a pro-Th17 immune response and related aspects. Further provided are methods of production of said compounds (I).
Carboxylation of benzylic and aliphatic C-H bonds with CO2 induced by light/ketone/nickel
Ishida, Naoki,Masuda, Yusuke,Imamura, Yuuya,Yamazaki, Katsushi,Murakami, Masahiro
supporting information, p. 19611 - 19615 (2019/12/24)
A photoinduced carboxylation reaction of benzylic and aliphatic C-H bonds with CO2 is developed. Toluene derivatives capture gaseous CO2 at the benzylic position to produce phenylacetic acid derivatives when irradiated with UV light in the presence of an aromatic ketone, a nickel complex, and potassium tert-butoxide. Cyclohexane reacts with CO2 to furnish cyclohexanecar-boxylic acid under analogous reaction conditions. The present photoinduced carboxylation reaction provides a direct access from readily available hydrocarbons to the corresponding carboxylic acids with one carbon extension.