88-68-6 Usage
Description
Anthranilamide, also known as 2-aminobenzamide, is an organic compound that serves as a versatile intermediate in the synthesis of various chemical products. It is characterized by its amide functional group and aromatic ring structure, which contribute to its diverse applications across different industries.
Uses
Used in Chemical Synthesis:
Anthranilamide is used as an intermediate for the production of dyes, pharmaceuticals, agricultural chemicals, perfumes, pigments, flavors, and organo luminophores. Its unique chemical structure allows for the creation of a wide range of products with various applications.
Used in PET Bottles:
Anthranilamide can be used as an acetyldehyde scavenger in PET bottles, as per a US patent by Coca-Cola. This application helps to improve the quality and safety of PET bottles by reducing the presence of acetyldehyde, a harmful substance.
Used in Lubricating Oils:
In the aerospace industry, anthranilamide is used in lubricating oils for supersonic jet engines to inhibit copper and magnesium corrosion. This application ensures the longevity and performance of the engine components.
Used in Manufacturing:
Anthranilamide is used in the manufacture of anthranilate esters and ion exchange resins, which have various applications in different industries, such as water treatment and chemical synthesis.
Used as a Lacquer Additive:
In the food packaging industry, anthranilamide can be used as a lacquer additive for food containers. This application helps to improve the durability and safety of food packaging materials.
Used as a Modifier for Alkyd Resins:
Anthranilamide can be used as a modifier to improve the drying of alkyd resins, which are used in coatings and paints. This application enhances the performance and efficiency of alkyd resin-based products.
Used as an Antioxidant:
In the lubricant industry, anthranilamide can be used as an antioxidant for greases, lube oils, and unsaturated rubbers. This application helps to extend the lifespan and performance of these materials by preventing oxidation and degradation.
Flammability and Explosibility
Nonflammable
Check Digit Verification of cas no
The CAS Registry Mumber 88-68-6 includes 5 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 2 digits, 8 and 8 respectively; the second part has 2 digits, 6 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 88-68:
(4*8)+(3*8)+(2*6)+(1*8)=76
76 % 10 = 6
So 88-68-6 is a valid CAS Registry Number.
InChI:InChI=1/C7H8N2O/c8-6-4-2-1-3-5(6)7(9)10/h1-4H,8H2,(H2,9,10)
88-68-6Relevant articles and documents
Glucose as an Eco-Friendly Reductant in a One-Pot Synthesis of 2,3-Dihydroquinazolin-4(1H)-ones
dos Santos, Thiago,Grundke, Caroline,Lucas, Tobias,Gro?mann, Luca,Clososki, Giuliano Cesar,Opatz, Till
supporting information, p. 6429 - 6432 (2020/09/02)
Carbohydrates such as glucose are an abundant renewable resource that can be employed in synthetic processes as a source of carbon and/or hydrogen to yield products of high economical and biological impact. Herein, we report a versatile and environmentally friendly protocol for the one-pot synthesis of 2,3-dihydroquinazolin-4(1H)-ones, a privileged scaffold in medicinal chemistry, based on the use of glucose as an eco-friendly reductant in alkaline aqueous medium. This method can be viewed as a blueprint for the development of further one-pot sequences involving glucose as a reductant.
Efficient Synthesis of Quinazolinones by Transition-Metal-Free Direct Aerobic Oxidative Cascade Annulation of Alcohols with o-Aminoarylnitriles
Wang, Qi,Lv, Miao,Liu, Jianping,Li, Yang,Xu, Qing,Zhang, Xu,Cao, Hongen
, p. 3043 - 3048 (2019/03/17)
A mild and atom-economic method was developed for direct and efficient synthesis of quinazolinones through a transition-metal-free aerobic oxidative cascade annulation reaction of widely available o-aminoarylnitriles and alcohols. Air could be employed as an effective oxidant under mild conditions, generating water as the only byproduct. Possibly owing to the “cesium effect”, the water-soluble base CsOH was found to be crucial in all key steps of the reaction mechanism. Because a wide range of substrates can be used to prepare substituted quinazolinones without contamination by transition-metal residues, this method may be of interest for application in pharmaceutical synthesis. Possible reaction paths were also proposed according to control reactions.
A copper catalyzed multicomponent cascade redox reaction for the synthesis of quinazolinones
Shinde, Mahesh H.,Kshirsagar, Umesh A.
, p. 52884 - 52887 (2016/06/14)
A copper catalyzed multicomponent cascade redox reaction for the synthesis of various quinazolinones starting from easily available 2-bromobenzamides, benzylic alcohols and sodium azide as a nitrogen source has been developed. The reaction involves copper catalyzed azidation of 2-bromobenzamide via an SNAr reaction and oxidation of benzyl alcohol followed by sequential reduction-condensation-oxidation to produce quinazolinones.