881-57-2Relevant articles and documents
Electrochemical detection of atrazine in wastewater samples by copper oxide (CuO) nanoparticles ionic liquid modified electrode
Karda?, Faruk,Beytur, Murat,Aky?ld?r?m, Onur,Yüksek, Haydar,Yola, Mehmet Lütfi,Atar, Necip
, p. 360 - 363 (2017)
In the present report, a new voltammetric sensor based on copper oxide nanoparticles involved in 2-(3-acetoxy-4-methoxybenzylidenamino)-thiophenol (AMT) ionic liquid (CuO NPs/ILs) was developed for atrazine (ATR) analysis. Firstly, the CuO NPs/ILs modifie
A modified Cu(0)-Cu(I)-mediated Caryl-CarylUllmann coupling for the synthesis of biaryls
Yasamut, Kittisak,Jongcharoenkamol, Jira,Ruchirawat, Somsak,Ploypradith, Poonsakdi
, p. 5994 - 6000 (2016/09/14)
A novel Cu(0)-Cu(I)-mediated Caryl-CarylUllmann coupling has been successfully developed. The use of Cu(I) salts allowed the reactions to proceed under relatively mild conditions (65?°C in DMSO for 15–72?h). The developed method was compatible with a relatively wide range of functional groups simultaneously present on the aromatic ring of different electronic nature. The aryl halides with an electron-withdrawing group ortho to the halide or an electron-donating group meta or para to the halide furnished the corresponding products in good to excellent yields (up to 98%).
Exploring the formation and recognition of an important G-quadruplex in a HIF1α promoter and its transcriptional inhibition by a benzo[c]phenanthridine derivative
Chen, Han,Long, Haitao,Cui, Xiaojie,Zhou, Jiang,Xu, Ming,Yuan, Gu
supporting information, p. 2583 - 2591 (2014/03/21)
Four putative G-quadruplex sequences (PGSs) in the HIF1α promoter and the 5′UTR were evaluated for their G-quadruplex-forming potential using ESI-MS, CD, FRET, DMS footprinting, and a polymerase stop assay. An important G-quadruplex (S1) has been proven to inhibit HIF1α transcription by blocking AP2 binding. A benzo[c]phenanthridine derivative was found to target the S1 G-quadruplex and induce its conformational conversion from antiparallel to parallel orientation. The transcriptional suppression of HIF1α by this compound was demonstrated using western blotting, Q-RT-PCR, luciferase assay, and ChIP. Our new findings provided a novel strategy for HIF1α regulation and potential insight for cancer therapy.