88149-57-9

Basic information

• Product Name: 1H-Pyrrole-3,4-dicarboxylic acid, 2,5-bis(trifluoromethyl)-, diethyl ester
• CAS NO: 88149-57-9
• Molecular Formula: C12H11F6NO4
• Molecular Weight: 347.214
• Mol File: 88149-57-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1H-Pyrrole-3,4-dicarboxylic acid, 2,5-bis(trifluoromethyl)-, diethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Pyrrole-3,4-dicarboxylic acid, 2,5-bis(trifluoromethyl)-, diethyl ester(88149-57-9)
• EPA Substance Registry System: 1H-Pyrrole-3,4-dicarboxylic acid, 2,5-bis(trifluoromethyl)-, diethyl ester(88149-57-9)

Safety Data

• Hazardous Substances Data: 88149-57-9(Hazardous Substances Data)

Upstream product

• 2757-23-5 chloro(chlorosulfanyl)methanone 
• 372-29-2 ethyl 3-amino-4,4,4-trifluoro-2-butenoate 

Relevant articles and documents

Syntheses and Reactions of 2-Halo-5-thiazolecarboxylates

A variety of 2-halo-5-thiazolecarboxylates was prepared from substituted-3-aminoacrylates and 3-ketoesters.Selective reduction of 2-chloro-5-thiazolecarboxylates 4a, 4i and 4j with sodium borohydride in ethanol provided the corresponding 2-halo-5-thiazolemethanols 27 - 29.Nucleophilic displacement on methyl methanesulfonate (32c) occured selectivity at the 5-substituent to provide 2-chloro-4-(trifluoromethyl)-5-(heteroatom-substituted methyl)thiazoles 32d-f.