881676-44-4

Basic information

• Product Name: 1H-Pyrrole-3-carboxaldehyde, 2-methyl-5-phenyl-1-(3-pyridinylsulfonyl)-
• CAS NO: 881676-44-4
• Molecular Formula: C17H14N2O3S
• Molecular Weight: 326.376
• Mol File: 881676-44-4.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 1H-Pyrrole-3-carboxaldehyde, 2-methyl-5-phenyl-1-(3-pyridinylsulfonyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Pyrrole-3-carboxaldehyde, 2-methyl-5-phenyl-1-(3-pyridinylsulfonyl)-(881676-44-4)
• EPA Substance Registry System: 1H-Pyrrole-3-carboxaldehyde, 2-methyl-5-phenyl-1-(3-pyridinylsulfonyl)-(881676-44-4)

Safety Data

• Hazardous Substances Data: 881676-44-4(Hazardous Substances Data)

Upstream product

• 114615-82-6 tetrapropylammonium perruthennate 
• 881675-59-8 ethyl 2-methyl-5-phenyl-1-(pyridin-3-ylsulfonyl)-1H-pyrrole-3-carboxylate 
• 70187-32-5 4-methylmorpholine 4-oxide monohydrate 
• 636-73-7 3-pyridinesulfonic acid 
• 881674-39-1 ethyl 5-bromo-2-methyl-1H-pyrrole-3-carboxylate 
• 936-12-9 2-methyl-1H-pyrrole-3-carboxylic acid ethyl ester 

Relevant articles and documents

Proton pump inhibitors

A proton pump inhibitor containing a compound represented by the formula (I) wherein X and Y are the same or different and each is a bond or a spacer having 1 to 20 carbon atoms in the main chain, R 1 is an optionally substituted hydrocarbon group or an optionally substituted heterocyclic group, R 2 , R 3 and R 4 are the same or different and each is a hydrogen atom, an optionally substituted hydrocarbon group, an optionally substituted thienyl group, an optionally substituted benzo[b]thienyl group, an optionally substituted furyl group, an optionally substituted pyridyl group, an optionally substituted pyrazolyl group, an optionally substituted pyrimidinyl group, an acyl group, a halogen atom, a cyano group or a nitro group, R 5 and R 6 are the same or different and each is a hydrogen atom or an optionally substituted hydrocarbon group, which has a superior proton pump action and shows an antiulcer activity and the like after conversion to a proton pump inhibitor in the body, or a salt thereof. or a prodrug thereof is provided.

Acid secretion inhibitor

The present invention provides a compound having a superior acid secretion inhibitory effect and showing an antiulcer activity and the like. The present invention provides a compound represented by the formula (I) wherein R1 is a nitrogen-containing monocyclic heterocyclic group optionally condensed with a benzene ring or a heterocycle, the nitrogen-containing monocyclic heterocyclic group optionally condensed with a benzene ring or a heterocycle optionally has substituent(s), R2 is an optionally substituted C6-14 aryl group, an optionally substituted thienyl group or an optionally substituted pyridyl group, R3 and R4 are each a hydrogen atom, or one of R3 and R4 is a hydrogen atom and the other is an optionally substituted lower alkyl group, an acyl group, a halogen atom, a cyano group or a nitro group, and R5 is an alkyl group or a salt thereof.