88287-77-8

Basic information

• Product Name: 4-Amino-3-(2,3,5-tri-O-benzyl-beta-ribofuranosyl)-5-pyrazole carbonitr ile
• Synonyms: 4-Amino-3-(2,3,5-tri-O-benzyl-beta-ribofuranosyl)-5-pyrazole carbonitr ile
• CAS NO: 88287-77-8
• Molecular Formula: C₃₀H₃₀N₄O₄
• Molecular Weight: 510.58
• Mol File: 88287-77-8.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 708.5°C at 760 mmHg
• Flash Point: 382.3°C
• Appearance: /
• Density: 1.3g/cm³
• Vapor Pressure: 6.37E-20mmHg at 25°C
• Refractive Index: 1.649
• CAS DataBase Reference: 4-Amino-3-(2,3,5-tri-O-benzyl-beta-ribofuranosyl)-5-pyrazole carbonitr ile(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Amino-3-(2,3,5-tri-O-benzyl-beta-ribofuranosyl)-5-pyrazole carbonitr ile(88287-77-8)
• EPA Substance Registry System: 4-Amino-3-(2,3,5-tri-O-benzyl-beta-ribofuranosyl)-5-pyrazole carbonitr ile(88287-77-8)

Safety Data

• Hazardous Substances Data: 88287-77-8(Hazardous Substances Data)

Usage

InChI:InChI=1/C30H30N4O4/c31-16-24-26(32)27(34-33-24)29-30(37-19-23-14-8-3-9-15-23)28(36-18-22-12-6-2-7-13-22)25(38-29)20-35-17-21-10-4-1-5-11-21/h1-15,25,28-30H,17-20,32H2,(H,33,34)/t25-,28-,29+,30-/m1/s1

Upstream product

• 88295-39-0 3-(2,3,5-Tri-O-benzyl-β-D-ribofuranosyl)-4-<<(2,2,2-trichloroethoxy)carbonyl>amino>pyrazole-5-carbonitrile 
• 88287-72-3 3-(2,3,5-Tri-O-benzyl-β-D-ribofuranosyl)-5-cyanopyrazole-4-carboxylic acid 
• 42890-06-2 (2R,3R,4R,5R)-3,4-bis(benzyloxy)-5-((benzyloxy)methyl)tetrahydrofuran-2-carboxylic acid 
• 117469-21-3 tert-butyl (Z)-3-cyano-3-(2,3,5-tri-O-benzyl-β-D-ribofuranosyl)propenoate 
• 117452-55-8 3-((2S,3S,4R,5R)-3,4-Bis-benzyloxy-5-benzyloxymethyl-tetrahydro-furan-2-yl)-5-cyano-1H-pyrazole-4-carbonyl chloride 
• 117452-52-5 3-((2S,3S,4R,5R)-3,4-Bis-benzyloxy-5-benzyloxymethyl-tetrahydro-furan-2-yl)-5-carbamoyl-1H-pyrazole-4-carboxylic acid tert-butyl ester 
• 117452-53-6 4-tert-butyloxycarbonyl-5-cyano-3-(2,3,5-tri-O-benzyl-β-D-ribofuranosyl)pyrazole 
• 117452-56-9 3-((2S,3S,4R,5R)-3,4-Bis-benzyloxy-5-benzyloxymethyl-tetrahydro-furan-2-yl)-5-cyano-1H-pyrazole-4-carbonyl azide 
• 117475-65-7 4-tert-butyloxycarbonyl-5-ethoxycarbonyl-3-(2,3,5-tri-O-benzyl-β-D-ribofuranosyl)pyrazole 
• 31083-47-3 Methyl 3-(2,3,5-tri-O-benzyl-β-D-ribofuranosyl)-5-carbamoylpyrazole-4-carboxylate 
• 88287-69-8 Methyl 3-(2,3,5-Tri-O-benzyl-β-D-ribofuranosyl)-5-cyanopyrazole-4-carboxylate 

Downstream Products

• 117452-60-5 3-(2,3,5-tri-O-benzyl-β-D-ribofuranosyl)pyrazolo<4,3-d>pyrimidine-5,7-thione 
• 88287-80-3 3-(2,3,5-Tri-O-benzyl-β-D-ribofuranosyl)-4-aminopyrazole-5-carbothiamide 
• 117452-59-2 5-cyano-4-diazo-3-(2,3,5-tri-O-benzyl-β-D-ribofuranosyl)pyrazole 
• 88287-86-9 3-(2,3,5-Tri-O-benzyl-β-D-ribofuranosyl)-5-(benzylthio)-7-aminopyrazolo<4,3-d>pyrimidine 
• 88287-85-8 N-[3-((2S,3S,4R,5R)-3,4-Bis-benzyloxy-5-benzyloxymethyl-tetrahydro-furan-2-yl)-7-thioxo-6,7-dihydro-1H-pyrazolo[4,3-d]pyrimidin-5-yl]-benzamide 
• 88287-84-7 4-(3-Benzoyl-2-benzyl-isothioureido)-5-((2S,3S,4R,5R)-3,4-bis-benzyloxy-5-benzyloxymethyl-tetrahydro-furan-2-yl)-2H-pyrazole-3-carbothioic acid amide 
• 80523-94-0 3-(2,3,5-Tri-O-benzyl-β-D-ribofuranosyl)-5-aminopyrazolo<4,3-d>pyrimidine-7-thione 

Relevant articles and documents

4-AMINO-3-(2,3,5-TRI-O-BENZYL-β-D-RIBOFURANOSYL)-5-PYRAZOLECARBONITRILE. SYNTHESIS AND CONVERSION INTO A SUGAR-BLOCKED 5,7-DISUBSTITUTED FORMYCIN ANALOG

The title compound, a potential intermediate to protected C-nucleoside analogs related to formycin A, was synthesized via a new route wherein 2,3,5-tri-O-benzyl-1-O-(p-nitrophenyl)-D-ribofuranose was converted to 2,5-anhydro-3,4,6-tri-O-benzyl-D-allonic a