883149-28-8

Basic information

• Product Name: N-(2-(1H-indol-3-yl)ethyl)-N-(2,4-dinitrobenzenesulfonyl)prop-2-yn-1-amine
• Synonyms: N-(2-(1H-indol-3-yl)ethyl)-N-(2,4-dinitrobenzenesulfonyl)prop-2-yn-1-amine
• CAS NO: 883149-28-8
• Molecular Weight: 428.425
• Mol File: 883149-28-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-(2-(1H-indol-3-yl)ethyl)-N-(2,4-dinitrobenzenesulfonyl)prop-2-yn-1-amine(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2-(1H-indol-3-yl)ethyl)-N-(2,4-dinitrobenzenesulfonyl)prop-2-yn-1-amine(883149-28-8)
• EPA Substance Registry System: N-(2-(1H-indol-3-yl)ethyl)-N-(2,4-dinitrobenzenesulfonyl)prop-2-yn-1-amine(883149-28-8)

Safety Data

• Hazardous Substances Data: 883149-28-8(Hazardous Substances Data)

Upstream product

• 61-54-1 tryptamine 
• 934479-33-1 N-(2-(1H-indol-3-yl)ethyl)-N-(2,4-dinitrobenzenesulfonyl)amine 
• 106-96-7 propargyl bromide 
• 1656-44-6 2,4-dinitrobenzenesulfonyl chloride 

Relevant articles and documents

Intra- and intermolecular reactions of indoles with alkynes catalyzed by gold

Indoles react intramolecularly with alkynes in the presence of gold catalysts to give from six- to eight-membered-ring annulated compounds. The cationic AuI complex [Au(P{C6H4-(o-Ph))(tBu) 2)(NCMe)]SbF6 is the best catalyst for the formation of six- and seven-membered rings by 6-endo-dig, 6-exo-dig, and 7-exo-dig cyclizations. Indoloazocines are selectively obtained with AuCl3 as catalyst in a rare 8-endodig process. In this process alienes or tetracyclic annulated derivatives are also formed as a result of an initial fragmentation reaction. The intermolecular reaction of indoles with alkynes proceeds to form 3-alkenylated intermediates that react with a second equivalent of indole to give bisindolyl derivatives. Indoles that are substituted at the 3-position react intermolecularly with alkynes to give 2-alkenylated intermediates that can be trapped intramolecularly with the appropriate nucleophiles.