88496-88-2 Usage
Description
Buntane-2-boronic acid is an organic compound that serves as a versatile reagent in organic synthesis, particularly in palladium-catalyzed cross-coupling reactions. It is known for its ability to form stable boron-containing intermediates, which are crucial for the formation of carbon-carbon bonds in various organic molecules.
Uses
Used in Pharmaceutical Industry:
Buntane-2-boronic acid is used as a reactant for the preparation of alkyland aryl quinones via silver nitrate-catalyzed coupling with quinones. This application is valuable in the synthesis of complex organic molecules, including those with potential pharmaceutical applications.
Used in Chemical Synthesis:
Buntane-2-boronic acid is used as a reactant for the preparation of arenes by coupling reactions with aryl bromides and chlorides in the presence of palladium complexes of a (pentaphenylferrocenyl)di(tert-butyl)phosphine. This method allows for the efficient formation of carbon-carbon bonds, which is essential in the synthesis of various organic compounds.
Used in Suzuki Reaction:
Buntane-2-boronic acid is used as a reactant in the Suzuki reaction, a widely employed palladium-catalyzed cross-coupling reaction between an organoboronic acid and an organohalide. This reaction is crucial for the formation of carbon-carbon bonds in a variety of organic molecules, including those with potential applications in materials science, pharmaceuticals, and agrochemicals.
Purification Methods
Purify the acid by recrystallisation from *C6H6/pet ether and dry in vacuo. [McCusker et al. J Am Chem Soc 79 5179 1957, Beilstein 4 IV 4386.]
Check Digit Verification of cas no
The CAS Registry Mumber 88496-88-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,8,4,9 and 6 respectively; the second part has 2 digits, 8 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 88496-88:
(7*8)+(6*8)+(5*4)+(4*9)+(3*6)+(2*8)+(1*8)=202
202 % 10 = 2
So 88496-88-2 is a valid CAS Registry Number.
InChI:InChI=1/C4H11BO2/c1-3-4(2)5(6)7/h4,6-7H,3H2,1-2H3
