885025-15-0Relevant articles and documents
Benzopyrans as selective estrogen receptor β agonists (SERBAs). Part 5: Combined A- and C-ring structure-activity relationship studies
Richardson, Timothy I.,Dodge, Jeffrey A.,Wang, Yong,Durbin, Jim D.,Krishnan, Venkatesh,Norman, Bryan H.
, p. 5563 - 5566 (2007)
Benzopyrans are selective estrogen receptor (ER) β agonists (SERBAs), which bind the ER subtypes α and β in opposite orientations. Here we describe the synthesis of a late stage intermediate that allowed us to combine A-ring and C-ring modifications and c