885315-17-3

Basic information

• Product Name: (+)-(S_S,S)-2-methyl-N-(2,2,2-trifluoro-1-phenylethyl)propane-2-sulfinamide
• Synonyms: (+)-(S_S,S)-2-methyl-N-(2,2,2-trifluoro-1-phenylethyl)propane-2-sulfinamide
• CAS NO: 885315-17-3
• Molecular Weight: 279.326
• Mol File: 885315-17-3.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: (+)-(S_S,S)-2-methyl-N-(2,2,2-trifluoro-1-phenylethyl)propane-2-sulfinamide(CAS DataBase Reference)
• NIST Chemistry Reference: (+)-(S_S,S)-2-methyl-N-(2,2,2-trifluoro-1-phenylethyl)propane-2-sulfinamide(885315-17-3)
• EPA Substance Registry System: (+)-(S_S,S)-2-methyl-N-(2,2,2-trifluoro-1-phenylethyl)propane-2-sulfinamide(885315-17-3)

Safety Data

• Hazardous Substances Data: 885315-17-3(Hazardous Substances Data)

Upstream product

• 929642-48-8 (S,E)-2-methyl-N-(2,2,2-trifluoroethylidene)propane-2-sulfinamide 
• 108-86-1 bromobenzene 
• 1219607-83-6 (S_S)-2-methyl-N-(2,2,2-trifluoroethylidene)-propane-2-sulfinamide 
• 75-46-7 trifluoromethan 
• 862776-58-7 (S)-N-benzylidene-2-methylpropane-2-sulfinamide 
• 100-52-7 benzaldehyde 
• 98-80-6 phenylboronic acid 
• 885315-11-7 2-Methyl-propane-2-sulfinic acid ((R)-1-ethoxy-2,2,2-trifluoro-ethyl)-amide 

Downstream Products

• 128404-37-5 (S)-2,2,2-trifluoro-1-phenylethan-1-amine hydrochloride 

Relevant articles and documents

Asymmetric addition reactions of Grignard reagents to chiral 2-trifluoromethyl tert-butyl (Ellman) sulfinimine-ethanol adducts

The addition of Grignard reagents to chiral trifluoromethyl tert-butyl sulfinimine-ethanol adducts affords protected trifluoromethylamines in high yields with good to excellent diastereoselectivities. The stereochemical outcome of the addition is opposite to that expected via a chelation controlled transition state.

METHOD FOR PRODUCING OPTICALLY ACTIVE TRIFLUOROMETHYL GROUP-CONTAINING AMINO ACID DERIVATIVE

PROBLEM TO BE SOLVED: To provide methods for producing optically active trifluoromethyl group-containing sulfinamide derivatives and optically active amino acids/hydrochlorides, using trifluoromethane as a generator of trifluoromethyl anions. SOLUTION: Th

Diastereoselective addition of organomagnesium and organolithium reagents to chiral trifluoromethyl N-tert-butanesulfinyl hemiaminals

The asymmetric synthesis of trifluoromethylated tertiary and secondary carbinamines (α,α-dibranched and α-branched amines) was achieved by reaction of alkyl, aryl and allyl organomagnesium or organolithium reagents to trifluoromethyl N-tert-butanesulfinyl