88547-15-3

Basic information

• Product Name: 2,5-Piperazinedione,3-methyl-,(3R)-(9CI)
• Synonyms: 2,5-Piperazinedione,3-methyl-,(3R)-(9CI);(R)-3-Methylpiperazine-2,5-dione
• CAS NO: 88547-15-3
• Molecular Formula: C₅H₈N₂O₂
• Molecular Weight: 128.13
• Product Categories: PIPERAZINE
• Mol File: 88547-15-3.mol
• Article Data: 11

Chemical Properties

• Melting Point: 247.5-249.5 °C
• Boiling Point: 495.7±38.0 °C(Predicted)
• Appearance: /
• Density: 1.149±0.06 g/cm3(Predicted)
• PKA: 13.22±0.40(Predicted)
• CAS DataBase Reference: 2,5-Piperazinedione,3-methyl-,(3R)-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 2,5-Piperazinedione,3-methyl-,(3R)-(9CI)(88547-15-3)
• EPA Substance Registry System: 2,5-Piperazinedione,3-methyl-,(3R)-(9CI)(88547-15-3)

Safety Data

• Hazardous Substances Data: 88547-15-3(Hazardous Substances Data)

Usage

Chemical structure

heterocyclic organic compound with a piperazine ring

Physical appearance

white to off-white crystalline solid

Uses

building block in the synthesis of pharmaceuticals and agrochemicals, valuable intermediate for the production of various other chemical compounds

Properties

may pose health and environmental hazards, handle with care

Upstream product

• 64395-12-6 3-methylene-piperazine-2,5-dione 
• 1188-01-8 dl-alanylglycine 
• 926-77-2 glycylalanine 
• 62-53-3 aniline 
• 338-69-2 D-Alanine 
• 56-40-6 glycine 
• 302-72-7 rac-Ala-OH 
• 4526-77-6 (S)-3-methyl-2,5-piperazinedione 
• 125719-12-2 (2-tert-Butoxycarbonylamino-propionylamino)-acetic acid ethyl ester 
• 107-21-1 ethylene glycol 
• 98524-00-6 protected dipeptide 
• 7732-18-5 water 
• 39748-65-7 N-(2-bromo-propionyl)-glycine amide 
• 84425-45-6 ethyl (2-chloroacetyl)alaninate 

Downstream Products

• 687-69-4 alanylglycine 
• 3695-73-6 glycyl-L-alanine 
• 88547-16-4 cyclo(-dehydrophenylalanyl-D-alanyl-) 
• 3997-90-8 D-ala-gly 
• 691-81-6 glycyl-(D)-alanine 
• 4526-77-6 L-alanylglycine diketopiperazine 
• 75336-86-6 (2R)-methylpiperazine 
• 182067-63-6 1,3,4-trimethylpiperazine-2,5-dione 
• 151369-36-7 3,6-Diethoxy-2,5-dihydro-2-methylpyrazine 
• 109-07-9 (RS)-2-methylpiperazine 
• 88489-21-8 cyclo(-(2R,3R)-phenylalanyl-2,3-d₂-D-alanyl-) 

Relevant articles and documents

EPIDITHIODIOXOPIPERAZINE COMPOUND OR ITS DERIVATIVES, AND THE USE THEREOF

The present invention relates to an epidithiodioxopiperazine derivative represented by the Chemical Formula 1 or its reduced derivative; a method for preparing a compound represented by Chemical Formula 1 having improved intracellular permeability and mim

Comparative study of synthetic approaches to 1- arylmethylenepyrazino[2,1-b]quinazoline-3,6-diones

The transformation of 3-arylmethylenepiperazine-2,5-diones (1) into 1- arylmethylene-2,4-dihydro-1H-pyrazino[2,1-b]quinazoline-3,6-diones (2) was studied. Four synthetic methods were compared, namely direct condensation with the product of the reaction be

Synthesis, Antibacterial Activities, and Pharmacological Properties of Enantiomers of Temafloxacin Hydrochloride

Temafloxacin hydrochloride is a potent member of the 4-pyridone-3-carboxylic acid class of antibacterial agents and is currently under clinical development as a broad-spectrum antimicrobial agent.It is a racemate having a chiral center at the C3 of the 7-piperazin-1-yl group.The two enantiomers were synthesized and tested for their antibacterial activities.Although no difference in in vitro antibacterial activities was observed, a minor difference in in vivo antibacterial activities was observed.However, they both exhibited similar pharmacological profiles.