887142-47-4

Basic information

• Product Name: 2-(5-bromomethyl-4-iodo-2-methyl-phenyl)-isoindole-1,3-dione
• Synonyms: 2-(5-bromomethyl-4-iodo-2-methyl-phenyl)-isoindole-1,3-dione
• CAS NO: 887142-47-4
• Molecular Weight: 456.077
• Mol File: 887142-47-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-(5-bromomethyl-4-iodo-2-methyl-phenyl)-isoindole-1,3-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(5-bromomethyl-4-iodo-2-methyl-phenyl)-isoindole-1,3-dione(887142-47-4)
• EPA Substance Registry System: 2-(5-bromomethyl-4-iodo-2-methyl-phenyl)-isoindole-1,3-dione(887142-47-4)

Safety Data

• Hazardous Substances Data: 887142-47-4(Hazardous Substances Data)

Upstream product

• 944263-04-1 2-[5-(tert-butyl-dimethyl-silanyloxymethyl)-4-iodo-2-methyl-phenyl]-isoindole-1,3-dione 
• 389091-74-1 5-(tert-butyl-dimethyl-silanyloxymethyl)-4-iodo-2-methyl-phenylamine 
• 81863-45-8 3-(hydroxymethyl)-6-methylaniline 
• 85-44-9 phthalic anhydride 
• 944262-94-6 2-(5-hydroxymethyl-4-iodo-2-methyl-phenyl)-isoindole-1,3-dione 

Downstream Products

• 887142-50-9 trifluoro-methanesulfonic acid 3-[5-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-2-iodo-4-methyl-benzyl]-2,2,6,6-tetramethyl-3,6-dihydro-2H-pyran-4-yl ester 
• 887142-49-6 2-[4-Iodo-2-methyl-5-((R)-2,2,6,6-tetramethyl-4-oxo-tetrahydro-pyran-3-ylmethyl)-phenyl]-isoindole-1,3-dione 
• 944262-95-7 2-(4-Iodo-5-{(S)-4-[(E)-(S)-2-methoxymethyl-pyrrolidin-1-ylimino]-2,2,6,6-tetramethyl-tetrahydro-pyran-3-ylmethyl}-2-methyl-phenyl)-isoindole-1,3-dione 

Relevant articles and documents

Indole diterpene synthetic studies. Total synthesis of (+)-nodulisporic acid F and construction of the heptacyclic cores of (+)-nodulisporic acids A and B and (-)-nodulisporic acid D

(Chemical Equation Presented) A first-generation strategy for construction of (+)-nodulisporic acids A (1) and B (2) is described. The strategy entails union of the eastern and western hemisphere subtargets via the indole synthesis protocol developed in our laboratory. Subsequent elaboration of rings E and F, however, revealed the considerable acid instability of the C(24) hydroxyl, thereby preventing further advancement. Nonetheless, preparation of the heptacyclic core of (+)-nodulisporic acids A and B, the total synthesis of (+)-nodulisporic acid F, the simplest member of the nodulisporic acid family, and elaboration of the heptacyclic core of (-)-nodulisporic acid D were achieved.